A Phase III, Open-Label, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Paclitaxel or Atezolizumab in Combination With Carboplatin+Nab-Paclitaxel Versus Carboplatin+Nab-Paclitaxel in Chemotherapy-Naive Patients With Stage IV Squamous Non-Small Cell Lung Cancer
A Phase III, Open-Label, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Paclitaxel or Atezolizumab in Combination With Carboplatin+Nab-Paclitaxel Versus Carboplatin+Nab-Paclitaxel in Chemotherapy-Naive Patients With Stage IV Squamous Non-Small Cell Lung Cancer
This randomized, open-label study will evaluate the safety and efficacy of atezolizumab (MPDL3280A) in combination with carboplatin + paclitaxel or carboplatin + nab-paclitaxel compared with treatment with carboplatin + nab-paclitaxel in chemotherapy-naive participants with Stage IV squamous NSCLC.
Inclusion Criteria:
Exclusion Criteria:
Sacramento, California 95825, United States
St. Petersburg, Florida 33705, United States
Carrollton, Georgia 30117, United States
Fairhaven, Massachusetts 02719, United States
Caxias do Sul, Rio Grande do Sul 95070-560, Brazil
Toulon, 83800, France
Minden, 32429, Germany
Villingen-Schwenningen, 78052, Germany
Petach Tiqwa, 4941492, Israel
Rambam, 3525408, Israel
Avellino, Campania 83100, Italy
Naples, Campania 80131, Italy
Naples, Campania 80131, Italy
Ehime, 791-0280, Japan
Fukuoka, 810-8563, Japan
Niigata, 951-8520, Japan
Satima, 362-0806, Japan
Moscovskaya Oblast, Moscow Oblast 143423, Russia
L'Hospitalet de Llobregat, Barcelona 08908, Spain
Santander, Cantabria 39008, Spain
Las Palmas de Gran Canaria, LAS Palmas 35016, Spain
S. Cristobal de La Laguna, Tenerife 38320, Spain
Madrid, 28050, Spain
Liuying Township, 736, Taiwan
Putzu, 613, Taiwan
Dnipropetrovsk, Katerynoslav Governorate 49102, Ukraine
Zaporizhzhya, Katerynoslav Governorate 69040, Ukraine
Kharkiv, Kharkiv Governorate 61070, Ukraine
Vinnytsia, KIEV Governorate 21029, Ukraine
Lviv, Volhynian Governorate 79031, Ukraine
Chernivtsi, 58013, Ukraine
Kryvyi Rih, 50048, Ukraine
Poltava, 36011, Ukraine