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Detecting scarred heart muscle is important to diagnose and treat of a wide variety of heart conditions. Magnetic resonance imaging (MRI) can assess scarred heart muscle but it is time consuming, contraindicated for some patients and not tolerated by others. Computed tomography (CT) imaging has the potential to provide a rapid comprehensive assessment of the heart. This study will assess CT imaging of the heart muscle of patients who have previously undergone MRI of their heart. Using a state of the art CT scanner the investigators will develop a low radiation dose protocol to identify scarred heart muscle. The investigators will use and develop software techniques to analyse these images. This will enable us to develop a new way to identify and measure scarred heart muscle that will benefit patients with heart disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants | Participants will have previously had an MRI scan and will undergo a CT scan. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computed tomography late enhancement imaging | Radiation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Myocardial late enhancement | The amount of myocardial late enhancement measured on computed tomography as compared to magnetic resonance imaging. | Immediate |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who have previously undergone magnetic resonance imaging which showed myocardial late enhancement.
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| Name | Affiliation | Role |
|---|---|---|
| Michelle Williams | University of Edinburgh, NHS Lothian | Principal Investigator |
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| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |