Genomic Predictors of Papillary Microcarcinoma Disease Progression

Genomic Predictors of Papillary Microcarcinoma Disease Progression

The study is being done to answer the following question: What are the specific clinical and molecular features that will help us predict which small thyroid cancers are likely to grow and be problematic?

Therefore, the purpose of this study is to identify specific clinical and molecular characteristics that are predictive of tumor progression in small thyroid cancers.

Inclusion Criteria:

• Biopsy proven papillary thyroid cancer (or suspicious for papillary thyroid cancer) confirmed by MSKCC cytopathologist.
• Being followed with active surveillance at MSKCC
• Biopsied index nodule less than or equal to 2 cm in maximum dimension
• Thyroid and neck US performed and interpreted by a MSKCC radiologist within 6 months prior to study entry.

Exclusion Criteria:

• Biopsied index nodule greater than 2 cm in any dimension
• Age less than 18 yrs old