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| ID | Type | Description | Link |
|---|---|---|---|
| 1012404 | Other Grant/Funding Number | Canadian Institutes of Health Research |
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| Name | Class |
|---|---|
| Canadian Institutes of Health Research (CIHR) | OTHER_GOV |
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The primary objective of this study is to determine whether baseline DOC screening can add to clinical and demographic data to predict the occurrence of a composite negative outcome (any of: recurrent stroke, myocardial infarction, death, or admission to a long-term care (LTC) / complex continuing care (CCC) facility) within one year of screening, in stroke prevention clinic patients.
The DOC screen will be routinely applied to all patients presenting to three high volume Regional Stroke Prevention Clinics (combined first visits >2,800 patients per year). Data will be abstracted from the patient chart using methodologies developed and validated in the Registry of the Ontario Stroke Network. The investigators have REB approval to collect this data and to link with administrative datasets through the Institute for Clinical and Evaluative Sciences (ICES). The investigators will use regression models to determine whether DOC screen scores add to baseline clinical and demographic data to predict the main negative outcomes. The investigators hope to identify which patients presenting to TIA/stroke prevention clinics are at highest risk of adverse long-term events so focused interventions can be developed to improve survival, outcomes and function of stroke prevention clinic patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Stroke Prevention Clinic Patients | All consecutive patients presenting to six high volume Regional Stroke Prevention Clinics. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with any Adverse Event | A composite negative outcome will be created, defined as the occurrence of any recurrent stroke, myocardial infarction, death, or admission to a long-term care (LTC) / complex continuing care (CCC) facility within one year of screening. | 1 Year from Initial Screen Date |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with recurrent stroke | The number of participants with the occurrence of recurrent stroke within one year of screening | 1 Year from Initial Screen Date |
| Incidence of DOC co-morbidities |
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Inclusion Criteria:
Exclusion Criteria:
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All consecutive patients attending outpatient Stroke Prevention and TIA Clinics.
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| Name | Affiliation | Role |
|---|---|---|
| Richard H Swartz, MD, PHD | Sunnybrook Health Sciences Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sunnybrook Health Sciences Centre | Toronto | Ontario | M4N 3M5 | Canada |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D002546 | Ischemic Attack, Transient |
| D003863 | Depression |
| D020181 | Sleep Apnea, Obstructive |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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To describe the incidence of DOC co-morbidities and outcomes in clinical important sub-groups (e.g. stroke-in-the-young, women vs. men, stroke in the "oldest-old" patients, TIA vs. ischemic stroke
| 1 Year from Initial Screen Date |
| Number of Participants with myocardial infarction | The number of participants with the occurrence of myocardial infarction within one year of screening | 1 Year from Initial Screen Date |
| Number of Participants who died | The number of participants who died within one year of screening | 1 Year from Initial Screen Date |
| Number of Participants who have been admitted to a long-term care or complex continuing care facility | The number of participants who have been admitted to a long-term care or complex continuing care facility within one year of screening | 1 Year from Initial Screen Date |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D002545 | Brain Ischemia |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |