The Effects of Morphine on Desflurane Consumption and Recovery Time

Comparison of Two Different Doses of Intravenous Morphine on Desflurane Consumption and Recovery Time in Patients Undergoing Total Abdominal Hysterectomy

Combination of volatile and opioid agents are used to achieve unconsciousness, haemodynamic stability and analgesia for surgical prosedures. This prospective, randomized, double-blind, controlled study evaluates the effects of two different doses of morphine sulphate (0.1 mg/kg and 0.2 mg/kg), on desflurane consumption, recovery characteristics, postoperative analgesic requirements and side effects during total abdominal hysterectomy.

Inclusion Criteria:

• undergoing total abdominal hysterectomy with general anaesthesia

Exclusion Criteria:

• renal dysfunction (cre>1.2), liver failure, cardiovascular, psychiatric, allergic and metabolic disorders