Vestibular Pain Interactions

Modulation of Pain Responses by Vestibular Stimulation. A Contact Heat Evoked Potential Study.

The goal is to establish the practical usefulness of vestibular stimulation for modulating pain perception and to describe the possible mechanisms that could underlie neural vestibular-somatosensory interactions.

Inclusion Criteria:

• Weight: 50 - 100 kg
• Height: 155 - 185 cm
• Male subjects 18 years to 60 years of age
• Sufficient command of German language
• Written informed consent by the participant after information about the project
• Without any known history of neurological disease (especially motor, somatosensory disorders, peripheral neuropathies).
• Right-handedness

Exclusion Criteria:

1. Intellectually or mental impaired subjects
2. Drug abuse
3. Chronic alcohol consumption
4. No use of marihuana 24h before measurements.
5. No history of vestibular or auditory disorders.
6. Diabetes mellitus
7. Participants of other studies during study period and 30 days prior to study begin
8. Any regular concomitant medication
9. Abnormal QST parameters at the baseline measurement.
10. Absent CHEPs-Potentials at the baseline measurement.