Comparison of Chitosan and Carboxymethylcellulose Silver Dressings on Burn Wounds in Pediatric and Adult Subjects

A Multi-Center, Randomized, Comparison Study of a Chitosan (Opticell Ag+) Silver Dressing and a Sodium Carboxymethylcellulose (Aquacel® Ag+) Silver Dressing on Burn Wounds in Pediatrics and Adults Subjects

The purpose of this prospective, randomized, comparative multi-center study is to compare the effective management of two silver-based dressings in managing exudative wounds in first and second degree burns.

Inclusion Criteria:

• Inpatient status at the site
• Written consent obtained from the subject
• Burn injury must have been incurred within 36 hours prior to enrollment.
• Burn injury must be of superficial partial thickness, mid-dermal partial thickness, or a combination of the two depths
• Burn injury must exceed 3% total body surface area.

Exclusion Criteria:

• Subject is pregnant.
• Bone fractures.
• Inhalation-related trauma.
• Sensitive and/or allergic to materials containing silver.
• Burn injury exceeds 40% total body surface area.
• Burn injury diagnosis indicates deep partial or full thickness wounds.
• Burn a result of electrical/chemical injury or frostbite.
• An active agent, such as a topical antimicrobial or an enzymatic debriding agent was previously used to treat the burn injury in question.