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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A01437-40 | Other Identifier | ID-RCB |
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The purpose of this study is to confirm the analgesic effect of tDCS in neuropathic chronic pain, to estimate the importance and the duration of this effect, and to improve its efficiency by the use at home.
It is established that the repetition of the sessions of cortical stimulation over a week improves their analgesic efficacy. However, this effect does not exceed a few weeks and is much lower than that of the stimulation implanted surgically. Implanted stimulation operates periodically, several times a day, and this "repetition of doses ", akin to the regular taking of a medicine, may explain its longer efficacy for pain relief which, may extend over several years (André-Obadia and al 2014).
No study at this date has estimated the long-term effect of non-invasive stimulation when is also periodically repeated on a daily basis, over several weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with neuropathic chronic pain | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| tDCS (use at home) | Device | During 4 weeks (every week : 20 minutes / day during 5 days) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Quality of sleep : numerical rating scale (NRS) from 0 (no sleep) to 10 (very good sleep). | over the week preceding the stimulation (W1), the period of ambulatory stimulation (W2-3-4-5) and the month according to the latter (W6-7-8-9-10) | |
| Fatigue : numerical rating scale (NRS) from 0 (exhausted) to 10 (very well) | over the week preceding the stimulation (W1), the period of ambulatory stimulation (W2-3-4-5) and the month according to the latter (W6-7-8-9-10) |
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Inclusion Criteria :
Exclusion Criteria :
(No limitation in the inclusion of male patients old enough to procreate).
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Luis Garcia-Larrea, Doctor | Contact | 4 72 35 78 88 | +33 | larrea@univ-lyon1.fr |
| Nathalie André-Obadia, Doctor | Contact | 4 72 35 70 68 | +33 | nathalie.obadia-andre@chu-lyon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon - Neurological Hospital - University Pain Clinic (CETD) | Recruiting | Bron | 69500 | France |
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| ID | Term |
|---|---|
| D009437 | Neuralgia |
| ID | Term |
|---|---|
| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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Efficacy will be assessed in a single-blind trial, with each patient receiving a series of "placebo" stimulations to check the clinical reality of the effects on pain.
| D009461 |
| Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |