Three Measures for the Prevention of Carious Lesions in Preschool Children

Study on Children's Dental Caries Prevention and Mechanism

Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children

Different caries prevention trials including fluoride vanish, IgY-passive immunotherapy and probiotics lasting 24 months were conducted with a total of 500 children aged 24 to 54 months of age in Lin'an, Zhejiang, China. The trials were cluster- domized .After obtaining parent´s informed consent, preschool children were clinical examinated according to ICDAS-Ⅱ and microbiological tested of saliva at baseline, 1m, 6m, 12m, 18m and 24m. To find the differences of caries incidence and oral microecology change in four groups, dmfs will be assessed and saliva will be analysed in experiment.

Inclusion Criteria:

• preschool children in good general health
• At least 18 deciduous teeth

Exclusion Criteria:

• With major systemic disease or on long-term medication
• Not cooperative and refuse dental treatment
• With a history of extra fluoride supplement
• Take antibiotics for nearly 8 weeks