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The aim of this study was to elucidate the accuracy and inter-rater agreement of diagnosis of nontuberculous mycobacterial lung disease based on chest computed tomography findings.
To elucidate the accuracy and inter-rater agreement of diagnosis of nontuberculous mycobacterial lung disease based on chest CT, two pulmonologists and two chest radiologists were requested to interpret chest CT of patients nontuberculous mycobacterial lung disease satisfying diagnostic criteria of American Thoracic Society as well as British Thoracic Society, or pulmonary tuberculosis. Two pulmonologists and two chest radiologists > 10 years of clinical experiences at a tertiary referral hospital participated as raters in this study. They were blinded to the any clinical information of the patients including the specific diagnosis, except age and sex. The interpretations of four raters were analyzed and compared.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nontuberculous lung disease | Patients with Nontuberculous Mycobacteria satisfying American Thoracic Society and British Thoracic Society guidelines | ||
| pulmonary tuberculosis | Patients with culture confirmed tuberculosis | ||
| bronchiectasis | Patients with bronchiectasis based on chest CT findings as well as symptoms |
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| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity for the diagnosis of nontuberculous mycobacterial lung disease | Percentage of cases diagnosed as nontuberculous mycobacterial lung disease by four raters out of confirmed cases with nontuberculous mycobacterial lung disease | baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Inter-rater correlation (kappa value) for the diagnosis of nontuberculous mycobacterial lung disease | Inter-rater correlation between four raters | baseline |
| Specificity for the diagnosis nontuberculous mycobacterial lung disease |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with nontuberculous mycobacterial lung diseases, pulmonary tuberculosis, bronchiectasis
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| Name | Affiliation | Role |
|---|---|---|
| Jae-Joon Yim, MD | Seoul National University Hospital | Principal Investigator |
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| ID | Term |
|---|---|
| D009165 | Mycobacterium Infections, Nontuberculous |
| ID | Term |
|---|---|
| D009164 | Mycobacterium Infections |
| D000193 | Actinomycetales Infections |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
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Percentage of cases diagnosed as other than nontuberculous mycobacterial lung disease by four raters out of confirmed cases with other than nontuberculous mycobacterial lung disease
| baseline |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |