The study is intended to assess the amount of crying and fussiness in infants fed an infant formula containing probiotics.

Inclusion Criteria:

• Singleton at birth
• Term infant with birth weight of 2500 g or more
• Crying or fussing for 3 or more hours per day
• Consuming mostly infant formula
• Signed Informed Consent and Protected Health Information authorization

Exclusion Criteria:

• Current use of extensively hydrolyzed or amino acid infant formula
• Planned use of probiotics during the study
• History of underlying metabolic or chronic disease, congenital malformation, or immunocompromised
• Enrollment in another interventional clinical research study