Endometriosis is one of the most common benign gynecological, affecting about 10% of premenopausal women. The pathophysiology of this disease is still not completely clear. Despite its prevalence, there is no blood test available for the diagnosis of endometriosis and the average delay time to diagnosis is 9.4 years.

Metabolomics is a scientific discipline that studies changes in metabolites related to the pathophysiology of the disease.

Aim of the study is to identify an alteration in the expression of the metabolites in women with endometriosis

Inclusion Criteria:

• women of childbearing age ;
• written consent to laparoscopic surgery;
• written consent to the study .

Exclusion Criteria:

• Suspicion or diagnosis of malignant disease
• Inability or unwillingness to provide written consent

women of childbearing age , patients of the University Hospital , suffering from benign gynecological disease