Effect of Xiaoer Jiebiao Oral Liquid on Hand-foot-mouth Disease

Effect and Safety of Xiao'er Jiebiao Oral Liquid in Combination With Standard Treatment on Hand-foot-mouth Disease in Pediatric Patients

This is a single-blinded randomized trial aiming to evaluate the effectiveness of Xiaoer Jiebiao Oral liquid in combination with Ribavirin treatment on patients with hand-foot-mouth disease compared with the controlgroup that recieve only libavirin treatment.

Inclusion Criteria:subjects should meet all of the following

• diagnosed as hand-foot-mouth disease grade I or grade II;
• body temperature at admission T>38℃，fever length<48 hours;
• no need for hormonotherapy or immunoglobulin therapy.
• signed written informed consent form

Exclusion Criteria:subjects should be excluded if meet any of the following

• with history of any heart, lung, kidney or liver diseases; under any hormonotherapy, immunoglobulin therapy or any other therapy.