The study will assess airway responses in mild atopic asthmatics undergoing repeat allergen challenge testing and will investigate whether ibuprofen changes the response.

Inclusion Criteria:

• diagnosis of mild asthma, currently well controlled requiring only a bronchodilator (e.g. salbutamol) as needed and infrequently
• has allergies that trigger asthma
• responds to methacholine challenge at 16mg/ml or less
• has FEV1 > 69.5% predicted

Exclusion Criteria:

• respiratory illness within 4 weeks
• other medical condition assessed by the principal investigator that would put the participant at risk or influence the integrity of the data
• pregnant or lactating females
• hypersensitivity to ibuprofen

journal publication