Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia

Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia: a Randomized Multicenter Controlled Trial (ACC Baxter)

The aim of this study is first to assess if desflurane is superior in order to achieve a faster emergence from anesthesia.

The aim of this study is first to assess if desflurane is superior in order to achieve a faster emergence from anesthesia (stating the date of birth) and second if desflurane is non-inferior in the occurrence of airway complications compared to sevoflurane or total intravenous anesthesia with propofol in the setting of laryngeal mask airway.

Inclusion Criteria:

• Planned anesthesia with use of LMA (laryngeal mask airway)
• Planned duration of anesthesia between 0.5 and 2 hours
• Age between 18-75 years
• Both gender
• Body mass index (BMI) <35
• ASA 1-3
• Written informed consent prior to study participation

Exclusion Criteria:

• Planned additional regional and local anesthesia
• Contra-indication for the use of a laryngeal mask airway
• Asthma
• COPD IV
• Known allergy or hypersensitivity to any drugs administered during this study
• Women who are pregnant, breast-feeding or women of childbearing potential not using adequate contraceptive methods
• Participation in a drug or device trial within the previous 30 days.
• Patients legally unable to give written informed consent.
• Patients with severe psychiatric disorders
• Recent (<6 months) history of alcohol or drug abuse
• Patients with severe neuropsychiatric disorders
• Non-fluency in German language