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| Name | Class |
|---|---|
| Oslo University Hospital | OTHER |
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The objective of this study is to explore the longitudinal course of self-disturbances (SD) in schizophrenia. The main aim of the study is to investigate, in a 6-7-year follow-up of a representative sample of patients with first-episode schizophrenia, bipolar disorder and other psychoses. The overall aim is to expand our knowledge about the role of SDs in psychotic disorders. Increased knowledge here will aid diagnosis and treatment. The current study is a seven year follow-up of this representative cohort, with baseline measures of SDs and a comprehensive clinical and neurocognitive assessment battery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Follow-Up Group | An earlier investigated cohort with first episode psychosis patients from two Norwegian counties. Being between 18 - 65 years old and being consecutive in- or outpatient referred to first adequate treatment for a DSM-IV diagnosis of schizophrenia, bipolar disorder, or "other psychosis". |
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| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in EASE (Examination of Anomalous Self-Experience)Total Score and Subscales of EASE | 6 year |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline for Structured Clinical Interview for the DSM ( SCID-I)(DSM-IV) | 6 year |
| Measure | Description | Time Frame |
|---|---|---|
| Change From Baseline in Positive and negative syndrome | Positive and Negative Syndrome Scale (PANSS) Total Score and Subscales of PANSS | 6 year |
| Change From Baseline in Calgary Depression Scale Score for Schizophrenia (CDSS) |
Inclusion Criteria:
Exclusion Criteria:
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Patients reffered to their first adequate treatment for broadly defines psychotic disorders (inkluding both schizophrenia - and bipolar Spectrum disorders) in Oppland and Hedmark counties in Norway, in 2008 - 2009 participated the base-line part of the study(E. Haug, 2012).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sykehuset Innlandet HF | Brumunddal | 2380 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25458477 | Background | Haug E, Oie M, Andreassen OA, Bratlien U, Nelson B, Aas M, Moller P, Melle I. Anomalous self-experience and childhood trauma in first-episode schizophrenia. Compr Psychiatry. 2015 Jan;56:35-41. doi: 10.1016/j.comppsych.2014.10.005. Epub 2014 Oct 16. | |
| 24378241 | Background | Haug E, Oie M, Andreassen OA, Bratlien U, Raballo A, Nelson B, Moller P, Melle I. Anomalous self-experiences contribute independently to social dysfunction in the early phases of schizophrenia and psychotic bipolar disorder. Compr Psychiatry. 2014 Apr;55(3):475-82. doi: 10.1016/j.comppsych.2013.11.010. Epub 2013 Nov 28. |
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| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D000341 | Affective Disorders, Psychotic |
| ID | Term |
|---|---|
| D001523 | Mental Disorders |
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Blood tests including cardiovascular risk factors and immunological parameters (cytokines).
| 6 year |
| Change from Baseline for Alcohol and Drug Use Disorder Identification Test (AUDIT and DUDIT) | 6 year |
| Change from Baseline for neurocognitive tests battery | 6 year |
| Change from Baseline for Global Assessment of Functioning - split Version(GAF) | 6 year |
| 22759943 | Background | Haug E, Lien L, Raballo A, Bratlien U, Oie M, Andreassen OA, Melle I, Moller P. Selective aggregation of self-disorders in first-treatment DSM-IV schizophrenia spectrum disorders. J Nerv Ment Dis. 2012 Jul;200(7):632-6. doi: 10.1097/NMD.0b013e31825bfd6f. |
| 22137461 | Background | Haug E, Oie M, Melle I, Andreassen OA, Raballo A, Bratlien U, Lien L, Moller P. The association between self-disorders and neurocognitive dysfunction in schizophrenia. Schizophr Res. 2012 Mar;135(1-3):79-83. doi: 10.1016/j.schres.2011.11.015. Epub 2011 Dec 3. |
| 21871617 | Background | Haug E, Melle I, Andreassen OA, Raballo A, Bratlien U, Oie M, Lien L, Moller P. The association between anomalous self-experience and suicidality in first-episode schizophrenia seems mediated by depression. Compr Psychiatry. 2012 Jul;53(5):456-60. doi: 10.1016/j.comppsych.2011.07.005. Epub 2011 Aug 25. |