This is a prospective study designed to evaluate the structural and functional integrity of transcatheter or surgical bioprosthetic valves with multimodality imaging. The study further aims to confirm resolution of the early bioprosthetic valve thrombotic changes with anticoagulation.

Patients with a history of bioprosthetic valve replacement undergo cardiac contrast CT imaging and transthoracic echocardiography to evaluate structural and functional integrity of the aortic valves. The imaging studies will be performed at least 48-hours after bioprosthetic valve replacement. Patients with prosthetic valve abnormalities suggestive of thrombus will be administered anticoagulation therapy, followed by repeat contrast CT of the chest and transthoracic imaging. Repeat imaging following 3 months of anticoagulation therapy is performed to evaluate the response to anticoagulation therapy. I

Inclusion Criteria:

• Presence of transcatheter or surgical bioprosthetic aortic valve implanted at least 48 hours prior to enrollment
• Age 18 years or older
• Ability to provide informed consent and follow-up with protocol procedures.

Exclusion Criteria:

• Renal insufficiency (creatinine > 1.5 mg/dL)
• Known allergy to iodinated contrast agents