"GOLIATH" - General Or Local Anaestesia in Intra Arterial THerapy

Anaesthetic Strategy During Endovascular Therapy: General Anaesthesia or Conscious Sedation ?

Patients suffering a stroke with a large vessel occlusion is often treated intra veneous thrombolyse and on top of that also intra arterial therapy. It is unknown what form of anaestesia is best during intra arterial therapy. The investigators will randomize these patients between general anaestesia and local anaestesia. Outcome will be growth of the ischemic lesion as judged on an MRI scan.

Inclusion Criteria:

• NIHSS>10
• mRS=<2
• groin puncture<6hours from stroke onset
• occlusion of ICA, ICA-T, M1, M2

Exclusion Criteria:

• MRI contraindications
• GCS<9
• intubated prior to arrival
• posterior circulation stroke
• allergy to anestetics