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This study aims to determine whether increasing atrial base rate pacing to achieve at least 75-80% atrial pacing in patients with sick sinus syndrome undergoing the implementation of dual-chamber pacemaker can be useful to prevent or decrease the atrial fibrillation during 6 months follow-up duration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Atrial Base Rate Pacing | Experimental | The base rate of pacemaker will be determined 75-100 beats/minute in condition that during first step of follow-up, his/her atrial pacing will be more than 80% of atrial high rate/automatic mode switch |
|
| Device Default | Active Comparator | The base rate of pacemaker will be determined 60 beats/minute |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HBR | Device |
|
| |
| DD |
| Measure | Description | Time Frame |
|---|---|---|
| Atrial high rate/Automatic mode switch episodes | The number of AHR/AMS episodes recorded by pacemaker | During 6 Months |
| Measure | Description | Time Frame |
|---|---|---|
| Stroke | The development of stroke during follow-up | During 6 months |
| Myocardial infarction | The development of MI during follow-up confirmed by ischemic chest pain, 12-ECG, or cardiac enzyme elevation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seyyed-al-Shohada Heart Center, UMSU | Urmia | West Azerbaijan Province | Iran |
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| ID | Term |
|---|---|
| D012804 | Sick Sinus Syndrome |
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001146 | Arrhythmia, Sinus |
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| Device |
|
|
| During 6 months |
| Heart failure | The development or progression of heart failure during follow-up | During 6 months |
| Worsening Functional Class | The worsening of functional class | During 6 months |
| Death | Death | During 6 months |
| D006327 |
| Heart Block |
| D000075224 | Cardiac Conduction System Disease |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |