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logistic reasons; amendment pending with IRB
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Rationale: Spinal anesthesia is a safe, frequently used anesthetic technique. The main side effect of spinal anesthesia is hypotension, occuring in up to 85 % of selected cases. This hypotension is often treated with fluid infusion. However, especially in elderly patients, high volume fluid infusion can lead to fluid overload.
The effects of spinal anesthesia on preload and fluid responsiveness are not exactly known. Hence, therapy for hypotension after spinal anesthesia might not be adequate. With transthoracic echocardiography, vena cava inferior diameter and collapsibility can be used to monitor fluid responsiveness and guide fluid management.
Objective: This study has two main objectives. The first is to explore the effects of spinal anesthesia on hemodynamic parameters of fluid status, especially vena cava inferior diameter and collapsibility. The second goal is to test the interrater variability transthoracic echocardiography exams when performed by (trained) anesthesiologists.
Furthermore, the correlation between vena cava inferior collapsibility and the occurence and degree of hypotension (defined as a decrease from baseline of >20% or a systolic pressure < 90 mmHg) after spinal anesthesia will be explored.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transthoracic echocardiography | Procedure | measurement of inferior vena cava diameter during inspiration and expiration using transthoracic echocardiography |
| Measure | Description | Time Frame |
|---|---|---|
| vena cava inferior collapsibility (in %) | vena cava inferior collapsibility: (Maximum vena cava inferior diameter - Minimum vena cava diameter)/maximum vena cava diameter | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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adult patients undergoing spinal anesthesia for minor surgery below the umbilicus
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| Name | Affiliation | Role |
|---|---|---|
| Arthur Bouwman, PhD | Catharina Ziekenhuis Eindhoven | Study Director |
| Harm Scholten, MD | Catharina Ziekenhuis Eindhoven | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Catharina Ziekenhuis Eindhoven | Eindhoven | North Brabant | 5623 EJ | Netherlands |
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| ID | Term |
|---|---|
| D007022 | Hypotension |
| D020896 | Hypovolemia |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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