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The patients undergoing axillary lymph node dissection were randomized into 3 groups: patients undergoing lavages with normal saline (Group 1), patients undergoing lavage gentamicin solution (Group 2) and patients undergoing lavage with a clindamycin solution (Group 3). Drainage volume discharge is investigated
The patients undergoing axillary lymph node dissection were randomized into 3 groups: patients undergoing 2 lavages with 500 ml normal saline (Group 1), patients first undergoing lavage with 500 ml normal saline followed by a second lavage with a 500 ml of a gentamicin (240 mg) solution (Group 2) and patients first undergoing lavage with 500 ml normal saline followed by a second lavage with 500ml of a clindamycin (600mg) solution (Group 3). Drainage volume discharge is investigated
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Irrigation with Gentamicin solution | Experimental | The surgical bed is irrigated with a gentamicin solution |
|
| Irrigation with Clindamycin solution | Experimental | The surgical bed is irrigated with a clindamycin solution |
|
| Irrigation with Normal saline | Placebo Comparator | The surgical bed is irrigated with normal saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Irrigation with gentamicin solution | Drug | The surgical bed is irrigated with a gentamicin solution |
|
| Measure | Description | Time Frame |
|---|---|---|
| Drainage volume discharge | 14 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jaime Ruiz-Tovar, MD, PhD | Hospital General de Elche | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26244837 | Derived | Oller I, Ruiz-Tovar J, Cansado P, Zubiaga L, Calpena R. Effect of Lavage with Gentamicin vs. Clindamycin vs. Physiologic Saline on Drainage Discharge of the Axillary Surgical Bed after Lymph Node Dissection. Surg Infect (Larchmt). 2015 Dec;16(6):781-4. doi: 10.1089/sur.2015.020. Epub 2015 Aug 5. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| ID | Term |
|---|---|
| D007507 | Therapeutic Irrigation |
| D000077330 | Saline Solution |
| ID | Term |
|---|---|
| D006875 | Hydrotherapy |
| D026741 | Physical Therapy Modalities |
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
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| Irrigation with Clindamycin solution | Drug | The surgical bed is irrigated with a clindamycin solution |
|
|
| Irrigation with Normal saline | Drug | The surgical bed is irrigated with normal saline |
|
|
| D017437 |
| Skin and Connective Tissue Diseases |
| D008919 |
| Investigative Techniques |
| D000077324 | Crystalloid Solutions |
| D007552 | Isotonic Solutions |
| D012996 | Solutions |
| D004364 | Pharmaceutical Preparations |