Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Understanding patient's prognosis is of utmost importance to determine radiotherapy's indication and dose/ fractionation. The investigators plan to conduct an observational study of prognosis of inpatients evaluated for palliative radiotherapy at a large cancer hospital in Brazil.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Palliative Patients | Inpatients evaluated for palliative radiation therapy. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival | Overall Survival in the studied population | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival in Each Indication of Palliative Radiotherapy | Overall Survival in Each Indication of Palliative Radiotherapy. The indication will be as follow:
| 3 months and 9 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Inpatients evaluated for palliative Radiation Therapy
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Heloisa A Carvalho, MD PhD | University of Sao Paulo | Study Director |
| Andre T Chen, MD | University of Sao Paulo | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto do Cancer do Estado de Sao Paulo, Hospital das Clinicas da Faculdade de Medicina da USP | São Paulo | 01246000 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10335930 | Background | Morita T, Tsunoda J, Inoue S, Chihara S. The Palliative Prognostic Index: a scoring system for survival prediction of terminally ill cancer patients. Support Care Cancer. 1999 May;7(3):128-33. doi: 10.1007/s005200050242. | |
| 19018082 | Background | Chow E, Abdolell M, Panzarella T, Harris K, Bezjak A, Warde P, Tannock I. Predictive model for survival in patients with advanced cancer. J Clin Oncol. 2008 Dec 20;26(36):5863-9. doi: 10.1200/JCO.2008.17.1363. Epub 2008 Nov 17. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009369 | Neoplasms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Overall Survival by Palliative Prognostic Index (PPI) |
Patients will be divided into 3 subgroups according to the PPI. Survival differences between the different subgroups will be compared and analyzed |
| 3 months and 9 months |
| Overall Survival by Survival Prognostic Score (SPS) | Patients will be divided into 3 subgroups according to the SPS. Survival differences between the different subgroups will be compared and analyzed | 3 months and 9 months |
| Overall Survival by Score Index for Stereotactic Radiosurgery for Brain Metastases (SIR) | Patients will brain metastases will be divided into 3 subgroups according to SIR. They will be divided into SIR 0-3; 4-7;8-10. Survival differences between the different subgroups will be compared and analyzed | 3 months and 9 months |
| Positive Predictive Value of PPI | Positive Predictive Value of PPI to predict death at 3 weeks and 6 weeks. | 3 weeks and 6 weeks |
| 11728693 | Background | Weltman E, Salvajoli JV, Brandt RA, de Morais Hanriot R, Prisco FE, Cruz JC, de Oliveira Borges S, Lagatta M, Ballas Wajsbrot D. Radiosurgery for brain metastases: who may not benefit? Int J Radiat Oncol Biol Phys. 2001 Dec 1;51(5):1320-7. doi: 10.1016/s0360-3016(01)01696-0. |
| 29625809 | Derived | Chen ATC, Mauro GP, Gabrielli F, Chaves CLG, Castro I, Vasconcelos KM, Reis M, Saraiva T, Carvalho HA. PROGRAD - An observational study of the prognosis of inpatients evaluated for palliative radiotherapy. Radiother Oncol. 2018 May;127(2):299-303. doi: 10.1016/j.radonc.2018.03.021. Epub 2018 Apr 3. |