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| Name | Class |
|---|---|
| University of Geneva, Switzerland | OTHER |
Objective:
To compare intraocular pressure lowering effect of combined sclerotomy ab interno with phacoemulsification and phacoemulsification alone, in primary or secondary open angle glaucoma patients.
Study design:
Prospective, randomized, case- control interventional surgical trial
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Combined sclerotomy ab interno and phaco | Experimental | Combined sclerotomy ab interno and phacoemulsification with IOL implantation |
|
| Phacoemulsification with IOL implantation | Active Comparator | Phacoemulsification with IOL implantation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Combined sclerotomy ab interno and phaco | Procedure |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Intraocular pressure | Baseline screening till 3 year post-op | |
| visual acuity | Baseline screening till 3 year post-op | |
| decrease in anti glaucoma medications | Baseline screening till 3 year post-op |
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Inclusion Criteria:
Patients suffering from primary open-angle glaucoma (POAG) inadequately controlled with maximum tolerated medical therapy and who will be treated with cataract surgery.
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lothar Knuenz | Contact | lothar.knuenz@oertli-instruments.com |
| Name | Affiliation | Role |
|---|---|---|
| Farhad Hafezi, MD, PhD | University of Geneva, Switzerland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Completed | Aswān | Egypt | ||||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20520572 | Background | Pajic B, Pajic-Eggspuehler B, Haefliger I. New minimally invasive, deep sclerotomy ab interno surgical procedure for glaucoma, six years of follow-up. J Glaucoma. 2011 Feb;20(2):109-14. doi: 10.1097/IJG.0b013e3181dddf31. |
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| Phacoemulsification with IOL implantation | Procedure |
|
|
| Recruiting |
| Kiel |
| Germany |
| Recruiting | Mumbai | India |
| Recruiting | Geneva | Switzerland |
| Recruiting | Reinach | Switzerland |
| ID | Term |
|---|---|
| D002386 | Cataract |
| D005901 | Glaucoma |
| ID | Term |
|---|---|
| D007905 | Lens Diseases |
| D005128 | Eye Diseases |
| D009798 | Ocular Hypertension |
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| ID | Term |
|---|---|
| D020742 | rhoA GTP-Binding Protein |
| D018918 | Phacoemulsification |
| D002387 | Cataract Extraction |
| ID | Term |
|---|---|
| D020741 | rho GTP-Binding Proteins |
| D020559 | Monomeric GTP-Binding Proteins |
| D019204 | GTP-Binding Proteins |
| D020558 | GTP Phosphohydrolases |
| D017766 | Acid Anhydride Hydrolases |
| D006867 | Hydrolases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D002352 | Carrier Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D047908 | Intracellular Signaling Peptides and Proteins |
| D054140 | Refractive Surgical Procedures |
| D013508 | Ophthalmologic Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D059708 | Ultrasonic Surgical Procedures |
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