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| Name | Class |
|---|---|
| Post Graduate Institute of Medical Education and Research, Chandigarh | OTHER |
| Luigi Sacco University Hospital | OTHER |
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This study is aimed at creation and validation of a vitreous haze scoring system using ultrasonography B-scan of the eye. Images will be obtained from patients with uveitis and quantification of inflammation will be done to create the scoring scale.
Patients with uveitis may present with Vitreous Haze (VH) resulting in obscuration of fundus details. VH is composed of cells and protein exudation and results in decrease visual acuity.The degree of VH is an important indicator of disease activity, severity and response to therapy in patients with uveitis. Color fundus images are commonly used to objectively document VH.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ultrasonography B-scan | Experimental | Patients of uveitis who are included in the study will be imaged using ultrasound B-scan |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasonography B-scan | Device | The patient's eye will be anesthetized. The ultrasound probe will then be used to obtain images by keeping the probe in light contact with the eye. |
| Measure | Description | Time Frame |
|---|---|---|
| Inter-observer correlation for vitreous haze grading | Inter-observer correlation for vitreous haze (VH) grading will be assessed using number of eyes as the unit of measure as well as standardized grading scheme for VH | 1 year |
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Inclusion Criteria:
• Ability to provide written informed consent and comply with study assessments for the full duration of the study
Exclusion Criteria:
• Patients with posterior segment complications including retinal detachment, choroidal detachment or hemorrhage
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| Name | Affiliation | Role |
|---|---|---|
| Quan D Nguyen, MD MSc | University of Nebraska | Principal Investigator |
| Giovanni Staurenghi, MD | Luigi Sacco Hospital | Principal Investigator |
| Ramandeep Singh, MS | Post Graduate Institute of Medical Education and Research, Chandigarh | Principal Investigator |
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| ID | Term |
|---|---|
| D014605 | Uveitis |
| ID | Term |
|---|---|
| D014603 | Uveal Diseases |
| D005128 | Eye Diseases |
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