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The aim of this cohort is to evaluate the follow-up of morbidly obese patients treated by several types of bariatric procedures. In addition, this study could lead to the development of clinical trials on assessment of the bariatric surgery impact.
The main objective is to prospectively evaluate long-term efficiency of bariatric surgery in terms of weight loss. Moreover, this cohort wants to assess the long-term effectiveness of bariatric surgery on comorbidities and quality of life, the medical and economic impact of bariatric surgery (before-after comparison using data from health insurance), estimates the incidence of mortality and morbidity of bariatric surgery and to finish describe the evolution of patients in case of new-surgery. From a methodological point of view, the Obesity cohort is a prospective cohort study, single-center, open, with aftercare performed during life of patients. The number of inclusions is to 1500 patients. After surgery , patients will be followed at least 4 visits the first year and at least 2 visits a year then. The recommendations of the french health ministry (HAS), the frequency of visits may be increased according to the patient's progress. Follow-up visits of patients after bariatric surgery will be performed by physicians or surgeons of the multidisciplinary team responsible for the care of the patient (digestive and reconstructive surgery, anesthesiology, endocrinology, medical imaging, gastroenterology, immunology and physiology) . It will be insured for life, obesity is a chronic disease and because of the risk of late complications.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group/Cohort | Other | all of the current bariatric surgeries are allowed in this prospective cohort study |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bariatric surgery | Procedure | all of the current bariatric surgeries are allowed in this prospective cohort study |
|
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of the long-term efficiency of bariatric surgery on weight loss | Assessment of weight loss | Change from intervention to 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of the long-term efficiency of bariatric surgery on diabetes | Assessment of blood glucose, HbA1c and diabetes medications | Change from intervention to 5 years |
| Assessment of the long-term efficiency of bariatric surgery on High Blood Pressure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David NOCCA, PUPH | Contact | 0467337731 | +33 | d-nocca@chu-montpellier.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU - Hôpital Saint Eloi | Recruiting | Montpellier | 34295 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37652841 | Derived | Saux P, Bauvin P, Raverdy V, Teigny J, Verkindt H, Soumphonphakdy T, Debert M, Jacobs A, Jacobs D, Monpellier V, Lee PC, Lim CH, Andersson-Assarsson JC, Carlsson L, Svensson PA, Galtier F, Dezfoulian G, Moldovanu M, Andrieux S, Couster J, Lepage M, Lembo E, Verrastro O, Robert M, Salminen P, Mingrone G, Peterli R, Cohen RV, Zerrweck C, Nocca D, Le Roux CW, Caiazzo R, Preux P, Pattou F. Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study. Lancet Digit Health. 2023 Oct;5(10):e692-e702. doi: 10.1016/S2589-7500(23)00135-8. Epub 2023 Aug 29. | |
| 35524904 |
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| ID | Term |
|---|---|
| D009767 | Obesity, Morbid |
| D015431 | Weight Loss |
| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
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| ID | Term |
|---|---|
| D050110 | Bariatric Surgery |
| ID | Term |
|---|---|
| D049088 | Bariatrics |
| D000073319 | Obesity Management |
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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Assessment of Systolic Blood Pressure and blood pressure medications |
| Change from intervention to 5 years |
| Assessment of the long-term efficiency of bariatric surgery on dyslipidemia | Assessment of cholesterolemia and triglyceridemia and dyslipidemia medications | Change from intervention to 5 years |
| Assessment of the long-term efficiency of bariatric surgery on rheumatism | Assessment of rheumatism medications | Change from intervention to 5 years |
| Assessment of the long-term efficiency of bariatric surgery on respiratory pathologies | Assessment of respiratory pathologies medications | Change from intervention to 5 years |
| Assessment of the long-term efficiency of bariatric surgery on sleep apnea syndrome | polysomnography tests | Change from intervention to 3 months |
| Assessment of the long-term efficiency of bariatric surgery on quality of life | Assessment of quality of life questionnaires (SF36 and BAROS) | Change from intervention to 5 years |
| Assessment of medico-economic impact of bariatric surgery | Comparison of health insurance data | Change from intervention to 5 years |
| Assessment of mortality of bariatric surgery | Assessment of the date of death | Change from intervention to 5 years |
| Derived |
| Nocca D, Galtier F, Taleb S, Picot MC, Jaussent A, Silvestri M, Lefebvre P, de Jong A, Gautier T, Loureiro M, Nedelcu M. Peri-operative Morbidity of Nissen Sleeve Gastrectomy: Prospective Evaluation of a Cohort of 365 Patients, Beyond the Learning Curve. Obes Surg. 2022 Jul;32(7):1-7. doi: 10.1007/s11695-022-06066-0. Epub 2022 May 7. |
| D009750 |
| Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001836 | Body Weight Changes |