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The aim of this split mouth study is to compare which method is better in reducing bone loss and healing times following implants. Specifically, the two methods investigated will be immediate gradual loading and early loading protocol.
Research Hypothesis Immediate gradual loading using gingival formers is superior to early loading protocols in improving bone quality and thus reducing the healing time.
These two methods (gradual loading and early loading) will both be used in implants patients with the aim to compare which protocol leads to a better outcome for the patient.
A 'better outcome' is defined as the method, which leads to the least crestal bone loss, and the fastest healing time.
Immediate gradually loaded side: will include transmucosal healing of dental implants using gingival formers which will be replaced every 2 weeks by consequent larger size gingival former.i.e. at surgery time the implants will receive 2 mm height gingival former which will be swapped by 3 mm, 4 mm, 5 mm and the last is 6 mm
early loaded side: implants will be submerged from the surgery time till loading time (2 month).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| implant A | Experimental | will include implants with immediate progressive loading using gingival formers of different sizes |
|
| implant B | Other | The implants will remain submerged from surgery time till loading time 2 month.(submerged healing) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| immediate progressive loading using gingival formers | Procedure | Implant placement will be 1 mm subcrestally, and it will receive transmucosal healing using gingival former. The gingival former will be replaced every 2 weeks by consequent larger size gingival former (at surgery time group A will receive 2 mm height gingival former which will be swapped by,3 mm, 4 mm and the last is 5 mm). |
| Measure | Description | Time Frame |
|---|---|---|
| secondary stability of dental implant (ISQ Osstell Mentol) | ISQ Osstell Mentol | 2 month |
| Measure | Description | Time Frame |
|---|---|---|
| Bone loss using Periapical Radiographic (Long Cone Paralleling technique) | using Periapical Radiographic (Long Cone Paralleling technique) | 2 month |
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Inclusion criteria
Exclusion criteria
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| elhassan mossad, oral surgeon | Contact | +201111113770 | mossadelhassan@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| elhassan mossad, oral surgeon | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of oral & Dental Medicine. Cairo University | Recruiting | Cairo | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15777325 | Background | Appleton RS, Nummikoski PV, Pigno MA, Cronin RJ, Chung KH. A radiographic assessment of progressive loading on bone around single osseointegrated implants in the posterior maxilla. Clin Oral Implants Res. 2005 Apr;16(2):161-7. doi: 10.1111/j.1600-0501.2004.01089.x. | |
| 16126077 | Background | Attard NJ, Zarb GA. Immediate and early implant loading protocols: a literature review of clinical studies. J Prosthet Dent. 2005 Sep;94(3):242-58. doi: 10.1016/j.prosdent.2005.04.015. |
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|
| submerged healing | Procedure | the implant placement will be 1 mm subcrestally, and it will receive unloaded healing.(submerged healing) |
|
| 16104954 | Background | Berglundh T, Abrahamsson I, Lindhe J. Bone reactions to longstanding functional load at implants: an experimental study in dogs. J Clin Periodontol. 2005 Sep;32(9):925-32. doi: 10.1111/j.1600-051X.2005.00747.x. |
| 16117773 | Background | Buchter A, Wiechmann D, Koerdt S, Wiesmann HP, Piffko J, Meyer U. Load-related implant reaction of mini-implants used for orthodontic anchorage. Clin Oral Implants Res. 2005 Aug;16(4):473-9. doi: 10.1111/j.1600-0501.2005.01149.x. |
| 15922992 | Background | Duyck J, Vandamme K, Geris L, Van Oosterwyck H, De Cooman M, Vandersloten J, Puers R, Naert I. The influence of micro-motion on the tissue differentiation around immediately loaded cylindrical turned titanium implants. Arch Oral Biol. 2006 Jan;51(1):1-9. doi: 10.1016/j.archoralbio.2005.04.003. Epub 2005 May 31. |
| 16219245 | Background | Duyck J, Vrielinck L, Lambrichts I, Abe Y, Schepers S, Politis C, Naert I. Biologic response of immediately versus delayed loaded implants supporting ill-fitting prostheses: an animal study. Clin Implant Dent Relat Res. 2005;7(3):150-8. doi: 10.1111/j.1708-8208.2005.tb00059.x. |
| 23724215 | Background | Ghoveizi R, Alikhasi M, Siadat MR, Siadat H, Sorouri M. A radiographic comparison of progressive and conventional loading on crestal bone loss and density in single dental implants: a randomized controlled trial study. J Dent (Tehran). 2013 Mar;10(2):155-63. Epub 2013 Mar 31. |
| 9638008 | Background | Isidor F. Mobility assessment with the Periotest system in relation to histologic findings of oral implants. Int J Oral Maxillofac Implants. 1998 May-Jun;13(3):377-83. |
| 9579618 | Background | Piattelli A, Corigliano M, Scarano A, Costigliola G, Paolantonio M. Immediate loading of titanium plasma-sprayed implants: an histologic analysis in monkeys. J Periodontol. 1998 Mar;69(3):321-7. doi: 10.1902/jop.1998.69.3.321. |
| 9249642 | Background | Piattelli A, Scarano A, Piattelli M, Bertolai R, Panzoni E. Histologic aspects of the bone and soft tissues surrounding three titanium non-submerged plasma-sprayed implants retrieved at autopsy: a case report. J Periodontol. 1997 Jul;68(7):694-700. doi: 10.1902/jop.1997.68.7.694. |
| 1657476 | Background | Soballe K, Hansen ES, Brockstedt-Rasmussen H, Hjortdal VE, Juhl GI, Pedersen CM, Hvid I, Bunger C. Gap healing enhanced by hydroxyapatite coating in dogs. Clin Orthop Relat Res. 1991 Nov;(272):300-7. |
| 11168189 | Background | Szmukler-Moncler S, Piattelli A, Favero GA, Dubruille JH. Considerations preliminary to the application of early and immediate loading protocols in dental implantology. Clin Oral Implants Res. 2000 Feb;11(1):12-25. doi: 10.1034/j.1600-0501.2000.011001012.x. |
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| 9588972 | Background | Misch CE, Hoar J, Beck G, Hazen R, Misch CM. A bone quality-based implant system: a preliminary report of stage I & stage II. Implant Dent. 1998;7(1):35-42. doi: 10.1097/00008505-199804000-00004. |
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| 8275378 | Background | Martin B. Aging and strength of bone as a structural material. Calcif Tissue Int. 1993;53 Suppl 1:S34-9; discussion S39-40. doi: 10.1007/BF01673400. |
| 15973947 | Background | Quinlan P, Nummikoski P, Schenk R, Cagna D, Mellonig J, Higginbottom F, Lang K, Buser D, Cochran D. Immediate and early loading of SLA ITI single-tooth implants: an in vivo study. Int J Oral Maxillofac Implants. 2005 May-Jun;20(3):360-70. |
| 3331974 | Background | Roberts WE, Turley PK, Brezniak N, Fielder PJ; New Collective Author. Implants: Bone physiology and metabolism. CDA J. 1987 Oct;15(10):54-61. No abstract available. |
| 18081870 | Background | Degidi M, Iezzi G, Scarano A, Piattelli A. Immediately loaded titanium implant with a tissue-stabilizing/maintaining design ('beyond platform switch') retrieved from man after 4 weeks: a histological and histomorphometrical evaluation. A case report. Clin Oral Implants Res. 2008 Mar;19(3):276-82. doi: 10.1111/j.1600-0501.2007.01449.x. Epub 2007 Dec 13. |
| 16123024 | Background | Diab T, Sit S, Kim D, Rho J, Vashishth D. Age-dependent fatigue behaviour of human cortical bone. Eur J Morphol. 2005 Feb-Apr;42(1-2):53-9. doi: 10.1080/09243860500095539. |
| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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