Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Psychiatric Hospital of the University of Basel | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim is to examine the effect of exercise (EX) training on individuals currently receiving ST - either opiate replacement therapy (ORT) or heroin-assisted treatment (HAT) - for their opiate dependence. Main outcome variables will be: cardiovascular fitness; consumption of substances (e.g. "street heroin", cocaine, cannabis, alcohol, cigarettes) other than prescribed ST or other prescribed medications; substance craving; blood pressure; lung function; resting pulse; social interaction; self-control capacity; objective and subjective sleep; cortisol levels; quality adjusted life years (QALYs); depression; mood. Covariates are current substitution dose and psychiatric diagnoses.
The investigators aim is to carry out a randomized controlled trial comparing exercise training group and a control group of patients receiving substitution therapy (ST). The specific goals of the study are:
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sport Group | Other | Participants randomised to the exercise condition will receive 12 weeks of physical exercise training. Once they have been assigned to this group, they will be informed about the training programme and its content. Training will be carried out in groups (two groups of ten or four groups of five, depending on scheduling, sport preferences, available materials) to ensure that individual attention can be paid to each participant. |
|
| Control Group | Other | The control group will not receive any exercise training. In order to control, as far as possible, for the potentially therapeutic effects of extra contact time with investigators, and the potentially motivational elements of participation in an intervention, the C group will have equal contact time with an investigator and participate in a leisure program without physical activity component. This time will be filled with group mealtimes, games, films, painting, handcrafts, stretching or relaxation exercises. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sport | Other |
| ||
| Non-sport activities |
| Measure | Description | Time Frame |
|---|---|---|
| Craving measured by the Brief Substance Craving Scale (translated) | Craving will be measured by the Brief Substance Craving Scale (translated) | 6 months |
| Secondary substance consumption assessed using the Time Line Follow Back method | This will be assessed using the Time Line Follow Back method | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Depression assessed using the Allgemeine Depressionskala ( Depression Scale) | Depression will be assessed using the Allgemeine Depressionskala ( Depression Scale) | 6 months |
| Self control measured using the Short Self Control Scale (translated) |
Not provided
Inclusion Criteria:
Patient at the Ambulanter Dienst Sucht or Janus clinics in Basel Town (BS); currently under substitution therapy
Exclusion Criteria:
Declared unfit to participate by clinic personnel due to physical disability or severe psychological disturbance or cognitive impairment
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Flora Colledge, PhD | Department for Sport, Exercise and Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department for Sport, Exercise and Health | Basel | 4052 | Switzerland |
Not provided
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
This will be measured using the Short Self Control Scale (translated)
| 6 months |
| Subjective sleep measured using the Insomnia Severity Index (translated) | This will be measured using the Insomnia Severity Index (translated) | 6 months |
| Physical activity level measured using the International Physical Activity Questionnaire | This will be measured using the International Physical Activity Questionnaire | 6 months |
| Perceived Stress measured using the Perceived Stress Scale (translated) | Will be measured using the Perceived Stress Scale (translated) | 6 months |
| Quality adjusted life years assessed using the Short Form (SF)36 questionnaire | This will be assessed using the Short Form (SF)36 questionnaire | 6 months |
| Blood pressure measured using a digital sphygmomanometer | This will be measured using a digital sphygmomanometer | 6 months |
| Lung function measured with a Spirobank Spirometer | Lung function will be measured with a Spirobank Spirometer | 6 months |
| Hand grip strength assessed using a Hydraulic Hand Dynamometer. | This will be assessed using a Hydraulic Hand Dynamometer. | 6 months |