Taste Properties of Atazanavir and Cobicistat

Assessment of the Taste Properties of Atazanavir and Cobicistat and Pediatric Oral Test Formulations Containing Both Atazanavir and Cobicistat in Healthy Adults

The primary objective is to assess the taste properties of atazanavir (ATV) and cobicistat (COBI) alone and in combination as well as oral test formulations containing both ATV and COBI.

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Inclusion Criteria:

• Men and women, ages ≥18 years
• Subjects who are qualified professional sensory panelists
• Healthy subjects as determined by no clinically significant deviation from normal in medical history and physical assessment

Exclusion Criteria:

• Any acute or chronic condition that may alter taste or smell sensory perception
• Any significant acute or chronic medical illness or any surgery within 4 weeks of the study drug administration
• Positive HIV test using an oral swab kit (such as OraQuick®) to detect HIV-1 or -2 antibody