Ocular Surface Dry Eye Microbiome

Microbiome Analysis of the Ocular Surface in Dry Eye Disease

The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses. Dry eye disease is thought to have an inflammatory basis and in the vast majority of cases the cause of the chronic inflammatory condition is unknown.

Inclusion Criteria:

• dry eye syndrome with OSDI score greater than 60
• control group with OSDI score less than 30

Exclusion Criteria:

• recent history of contact lens wear
• use of topical antibiotics or prescription eye medication in past 6 months
• penetrating ocular surgery in the last 12 months
• age less than 18 years