Bleeding Prediction in Thrombocytopenia

Bleeding Prediction in Thrombocytopenia Using Platelet Indices, Platelet Aggregometry and a Standardized Bleeding Questionnaire

The purpose of the study is to investigate whether platelet indices from automated haematology equipment, whole blood impedance aggregometry and a standardized bleeding questionnaire predict bleeding in admitted patients with thrombocytopenia of various causes.

Thrombocytopenia is a risk factor for bleeding, but studies concerning markers for stratification of bleeding risk among thrombocytopenic patients are lacking. This prospective observational cohort study investigates risk factor for bleeding in admitted patients with thrombocytopenia of various causes.

Inclusion Criteria:

• Admitted patients with thrombocytopenia
• Age ≥18 years
• Platelet count below 80 x109/L

Exclusion Criteria:

• Platelet transfusion within the previous 14 days,
• surgery or trauma within the previous 7 days
• Unable to give informed consent.