Historical Data Analysis of Complete Remission in Children With R/R Acute Lymphoblastic Leukemia (ALL)

A Retrospective Pooled Analysis of Complete Remission Among Pediatric Patients With Relapsed or Refractory B-cell Precursor Acute Lymphoblastic Leukemia (ALL)

An historical data comparator study for children with relapsed/refactory acute lymphoblastic leukemia (ALL).

A retrospective observational study reviewing historical complete remission for pediatric patients who had either relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL)

Inclusion criteria:

• Pediatric (age less than 18 years) patients with relapsed or refractory B-cell precursor ALL, specifically those with
• 2nd or later relapse after chemotherapy (with no prior transplantation),
• Relapse after HSCT, or
• Refractory disease
• Had treatment for relapsed or refractory disease between 2005-2012
• Has data available on ALL treatment, including number of salvage treatments, response status after therapies, and HSCT

Exclusion criteria:

• No CNS involvement at relapse
• No previous treatment with blinatumomab