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The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Functional autonomy level collection | Experimental | Collection of the Functional autonomy level every 6 - 12 months by phone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6 | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Functional autonomy level | The scores of "Lawton Instrumental Activities of Daily Living" (IADL) and of "Disability Assessment of Dementia" (DAD-6) | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive function level | Mini Mental Test examination (MMSE) | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pierre Krolak-Salmon, Professor | Contact | (0)4 72 43 20 50 | +33 | pierre.krolak-salmon@chu-lyon.fr |
| Virginie Dauphinot, Doctor | Contact | (0)4 72 43 20 50 | +33 | virginie.dauphinot@chu-lyon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Dugoujon | Not yet recruiting | Caluire-et-Cuire | 69300 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31319809 | Derived | Dauphinot V, Moutet C, Rouch I, Verdurand M, Mouchoux C, Delphin-Combe F, Gaujard S, Krolak-Salmon P; MEMORA group. A multicenter cohort study to investigate the factors associated with functional autonomy change in patients with cognitive complaint or neurocognitive disorders: the MEMORA study protocol. BMC Geriatr. 2019 Jul 18;19(1):191. doi: 10.1186/s12877-019-1204-1. |
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| ID | Term |
|---|---|
| D008569 | Memory Disorders |
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| Hospices Civils de Lyon - Hôpital des Charpennes | Recruiting | Lyon | France |
|
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D024801 | Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |