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After cardiac surgery, many complications can arise, in particular at the cardiac and lung level and it is true especially as the patient is with comorbidity. A patient will be considered at risk of a cardiac surgery if risk factors are present in preoperative (obesity, Chronic obstructive pulmonary disease (COPD), etc...). The non-invasive ventilation (NIV)developed these last years in the treatment of acute cardiac insufficiency and the hypercapnic COPD exacerbations; its use is more and more envisaged in cardio-thoracic and abdominal surgery services.
Studies showed that the NIV allowed an improvement of the oxygenation, the lung volumes and a decrease of ventilation work. According to these observations, the preventive NIV could reduce the incidence of appearance of the lung and/or cardiac complications at the patients to risk. we estimate 40 to 50%of cardiac surgery patients at a high risk level and we expect to obtain a benefit with this particular population. If we meet our goal (a significant difference in terms of morbi-mortality with the preventive NIV versus classical care), we expect the systematisation of this procedure to all cardiac surgery high risk patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Manufacturer STELLAR 150 | Experimental | 5 days of non-invasive ventilation at two levels of pressure from it pre-operative, followed by 5 days in post-operative. |
|
| Control Group | No Intervention | Standard preparation |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Manufacturer STELLAR 150 | Device | 5 days of non-invasive ventilation at two levels of pressure from it pre-operative, followed by 5 days in post-operative. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Appearance of cardio-pulmonary complications in postoperative cardiac surgery | Appearance of cardio-pulmonary complications in postoperative cardiac surgery among the complications listed below:
| 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Determine postoperative mortality; length of stay in intensive care, length of stay in the service of CCTV | 1 and 3 month |
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Inclusion Criteria:
Every patient of more than 18 years, programmed for a cardiac surgery ( valve replacement, coronary bypass, aortic surgery) in the service of "Chirurgie Cardio-Thoracique et Vasculaire" (CCTV) of the CHRU of Brest
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Francis COUTURAUD, Pr | Département de Médecine Interne et de Pneumologie, CHU BREST | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Brest | Brest | 29200 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39984118 | Derived | Goret M, Pluchon K, Le Mao R, Badra A, Oilleau JF, Morvan Y, Beaumont M, Desanglois G, Guegan M, Barnier A, Gut-Gobert C, Tromeur C, Leroyer C, Choplain JN, Khalifa A, Bezon E, Couturaud F. Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications: A Clinical Randomized Trial. Chest. 2025 Jun;167(6):1727-1736. doi: 10.1016/j.chest.2025.02.010. Epub 2025 Feb 19. |
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