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This is a study intended to evaluate a non-invasive device that uses light to measure the amount of oxygen in the muscles of injured and non-injured legs in specific situations. The name of this technology is NIRS (near-infrared spectroscopy). The goal of this study is to collect the information necessary to understand the use of the NIRS monitoring system to diagnose and direct treatment decisions in case of complications sometimes experienced in traumatic tibia fracture, such as excessive swelling called acute compartment syndrome (ACS).
This study seeks to further develop the use of NIRS technology in the diagnosis of acute compartment syndrome. NIRS values normally increase in traumatized legs compared to the contralateral uninjured leg or forearm, indicative of a hyperemic response. The investigators hopes to build upon the current knowledge and verify the ability to accurately detect ACS using two easily identified and accessible leg compartments, the anterior and superficial posterior utilizing the Nonin 7600 oximeter with the Sensor Model 8004CV. Additionally, since this device was originally designed with brain tissue in mind, the NIRS device will collect vital engineering data that will be used to validate the algorithm used to produce the oxygenation values in injured muscle tissue.
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| Measure | Description | Time Frame |
|---|---|---|
| NIRS measurements as compared to clinical findings | Assess the accuracy of the Nonin 7600 oximeter with the Sensor Model 8004CV in the diagnosis of Acute Compartment Syndrome, using the "gold standard" criterion for ACS, which will be "clinical diagnosis". That is, all subjects undergoing fasciotomy for clinically diagnosed ACS will be considered to have ACS. NIRS values will be compared to clinical diagnosis to determine accuracy and threshold values. | Participants will be followed for the duration of hospital stay, an expected average of 72 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of NIRS measurements compared to Intracompartmental pressure (ICP) measurements | ICP measurements will be compared to NIRS values to assess the magnitude of accuracy between the 2 tools. | Participants will be followed for the duration of hospital stay, an expected average of 72 hours |
| Correlation between NIRS measurements between injured and uninjured extremity |
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Inclusion Criteria:
Anatomic location:
High Energy Mechanism of Injury:
Exclusion Criteria:
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Subjects will be recruited from the trauma bay, surgical wards and ICU of Grady Memorial Hospital.
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| Name | Affiliation | Role |
|---|---|---|
| William Reisman, MD | Emory University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | United States |
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| ID | Term |
|---|---|
| D009140 | Musculoskeletal Diseases |
| D013978 | Tibial Fractures |
| ID | Term |
|---|---|
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D007869 | Leg Injuries |
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Compare NIRS values between non-injured and injured extremities |
| Participants will be followed for the duration of hospital stay, an expected average of 72 hours |