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| Name | Class |
|---|---|
| Hamilton Health Sciences Corporation | OTHER |
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A prospective cohort pilot study of non-cardiac patients to determine the feasibility of recruiting 150 patients to undergo postoperative continuous hemodynamic monitoring for up to 3 days.
Patient will start wearing the Philips' hemodynamic and ECG monitor in the Post Anaesthesia Care Unit (PACU). This device will continuously measure heart rate, pulse oxymetry, and ST-segments. The device will measure blood pressure every hour from 7 am to 10 pm and every 2 hours from 10 pm to 7 am.
Patients will have postoperative Troponin I monitoring and telephone follow-up at 30 days postop.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ECG, blood pressure and oximetry | Other |
| Measure | Description | Time Frame |
|---|---|---|
| Hypotension and Hypoxemia (baseline patterns and frequencies) | To identify baseline patterns and frequencies of hypotension and hypoxemia. | 10 months |
| Measure | Description | Time Frame |
|---|---|---|
| Myocardial Ischemia (association between myocardial ischemia detected by the algorithm implemented by MX40 with Troponin I) | To determine the association between myocardial ischemia detected by the algorithm implemented by MX40 with Troponin I. | 10 months |
| Myocardial Ischemia (delay in detecting myocardial ischemia based on MX40 monitoring versus Troponin I monitoring) |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain (association between postoperative pain intensity and myocardial ischemia, nonfatal myocardial infarction, and cardiac mortality) | To determine the association between postoperative pain intensity and myocardial ischemia, nonfatal myocardial infarction, and cardiac mortality. | 10 months |
Inclusion Criteria: We will enroll patients aged 45 years or older undergoing noncardiac surgery who fulfilled 2 or more of the following risk factors:
Exclusion Criteria:
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Patients aged 45 or greater who present for noncardiac surgery with 2 or more risk factors for heart disease and will be receiving a general or spinal anesthesia with an anticipated length of stay of 3 days or more.
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| Name | Affiliation | Role |
|---|---|---|
| Philip J. Devereaux, MD, PhD | McMaster University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Juravinski Hospital | Hamilton | Ontario | L8V5C2 | Canada |
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| ID | Term |
|---|---|
| C062669 | epicatechin gallate |
| D001794 | Blood Pressure |
| D010092 | Oximetry |
| ID | Term |
|---|---|
| D055986 | Vital Signs |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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To determine the delay in detecting myocardial ischemia based on MX40 monitoring versus Troponin I monitoring. |
| 10 months |
| Myocardial Ischemia (number of patients with missed clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring) | To determine the number of patients with missed clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring. | 10 months |
| Myocardial Ischemia (delay in detecting clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring.) | To determine the delay in detecting clinically important hypotension, bradycardia, and hypoxia based on routine monitoring in clinical practice versus remote, automated, non-invasive hemodynamic monitoring. | 10 months |
| D006439 |
| Hemodynamics |
| D002320 | Cardiovascular Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |
| D001784 | Blood Gas Analysis |
| D001774 | Blood Chemical Analysis |
| D019963 | Clinical Chemistry Tests |
| D019411 | Clinical Laboratory Techniques |
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D012129 | Respiratory Function Tests |
| D003948 | Diagnostic Techniques, Respiratory System |
| D008919 | Investigative Techniques |