Study of Interventional Pulmonologic Treatment of Malignant Central Airway Stricture

Prospective, Open, Multicenter Study of Interventional Pulmonologic Treatment of Malignant Central Airway Stricture

The purpose of this study is to evaluate the efficacy and safety of four interventional pulmonology techniques for the treatment of malignant central airway stricture.

The four techniques are：

• cryotherapy
• argon plasma coagulation
• stent
• snare

Inclusion Criteria:

• malignant neoplasm caused central airway stenosis
• the degree of stenosis is above 50%
• estimated survival duration is longer than 3 months
• received no treatment one month before
• can understand the statement informed consent
• agree to enroll in the study

Exclusion Criteria:

• older than 70 years or younger than 18 years
• not malignant neoplasm caused central airway stenosis
• not central airway stenosis
• existence of lumina collapse or twisting
• severe arrhythmia, myocardial ischemia or hypertensive crisis
• coagulation disorders
• existence of severe organ disfunction
• allergic to anesthesia drugs
• refuse to participate the study