All patients undergoing emergent endotracheal intubation (RSI) at the Emergency Department will be screened for inclusion in this clinical study. The indication of endotracheal intubation is an exclusively clinical decision and is not affected by this study protocol in any aspect.

If fulfilling the In- and exclusion criteria's, patient will be randomly assigned to one of two groups

1. C-MAC Videolaryngoscope in appropriate size
2. conventional endotracheal intubation using Macintosh Blade in appropriate size

Randomization (1:1) will be based on computer-generated codes maintained in sequentially numbered opaque envelopes that will be opened immediately before randomization.

Inclusion Criteria:

• Patients requiring emergency Rapid Sequence Intubation at the emergency department
• Male and Female subjects 18 years to 99 years of age
• Written confirmation by a physician not involved in this study
• Written informed consent by the participant (obtained afterwards)
• Patient not showing remarkable rejection in participation in this study

Exclusion Criteria:

• Maxilla-Facial trauma
• Immobilized cervical spine
• Indication for fiberoptic guided intubation (known difficult airway)
• Ongoing Cardio-Pulmonary-Resuscitation (CPR)
• Involvement in any other clinical trial during the course of this trial, within a period of 30 days prior to its beginning or 30 days after its completion
• Severe or immediately life-treating injury requiring immediate medical treatment