Impact of Obstructive Sleep Apnea Treatment in Patients With Metabolic Syndrome

Impact of Obstructive Sleep Apnea Treatment in Patients With Metabolic Syndrome: A Randomized Study

Obstructive Sleep Apnea (OSA) is a common condition that may induce hemodynamic and metabolic dysregulation. However, it is not clear if OSA is a mere epiphenomenon or contributes to increase the morbidity associated with metabolic syndrome. This study was designed to evaluate the impact of OSA treatment with CPAP in consecutive patients with metabolic syndrome.

Inclusion Criteria:

• Metabolic Syndrome (ATP III)
• Moderate to severe OSA

Exclusion Criteria:

• Smokers
• Patients under chronic use of medications
• Neurological diseases
• Coronary artery disease
• Acute heart failure
• Chronic renal failure (GFR < 30 ml/min)
• Chronic obstructive pulmonary disease
• Mild OSA and patients with BMI over 40 kg/m2.