Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Conselho Nacional de Desenvolvimento CientĆfico e Tecnológico | OTHER_GOV |
| Fundação de Amparo à Pesquisa do estado de Minas Gerais | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of the study is find out the better measure to achieve corneal protection in an Intensive Care Unit.
Critically ill patients are at higher risk for corneal injury and the mechanisms responsible for ocular lubrication and protection can be compromised. However, the literature diverges on which is the best clinical practice for treatment. There is a scale for assessing the risk for corneal injury. Thus, the general objective of this study was to evaluate the risk for developing corneal injury in critically ill patients and the effectiveness of three types of interventions: eye gel, eyedrops and polyethylene film, compared to the control group in its prevention. The specific objectives were: verify the most effective intervention for the prevention of corneal injury from the available literature and provided by: eye gel, eyedrops and polyethylene film compared to the control group who received eye care through randomized controlled clinical trial. Patients and methods: This study was a randomized controlled trial to determine the best care for the prevention of corneal injury from those available on the market (eye drops, eye gel and polyethylene film), compared to a control group (eye care) in the period from 09/07/2013 to 03/15/2014 .
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Eye drop | Sham Comparator | Eye drop LACRIBELLĀ® - two drops each eye, three times a day, after eye cleansing. |
|
| Ocular gel | Sham Comparator | Ocular gel LIPOSICĀ® applied three times a day at the lower palpebra from medium line to the lateral border. |
|
| Glad wrap | Sham Comparator | Occlusion of the orbital area with a Glad wrap, turning the area into a moisture chamber. |
|
| Control group | No Intervention | Ocular cleansing three times a day. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LACRIBELLĀ® | Device | Hypromellose and dextran based eyedrop, used in the treatment of dry eye. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Keratitis | Presence of keratitis visible with a cobalt light ophthalmoscope and fluorescein eye drop. | Five days |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Andreza Werli-Alvarenga, RN, MD, PhD | Hospital Risoleta Tolentino Neves | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Risoleta Tolentino Neves | Belo Horizonte | Minas Gerais | 31744012 | Brazil |
Not provided
Not provided
Not provided
Not provided
Not provided
| LIPOSICĀ® | Device | Carbomer and Sorbitol based gel, used in the treatment of dry eye. |
|
|
| Glad wrap | Device | A clear plastic wrap occluding eye and orbital area, turning the space into a moisture chamber. |
|
|
| ID | Term |
|---|---|
| D007634 | Keratitis |
| D003320 | Corneal Ulcer |
| D003316 | Corneal Diseases |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D015817 | Eye Infections |
| D007239 | Infections |
Not provided
Not provided