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| Name | Class |
|---|---|
| Johns Hopkins University | OTHER |
| University of Tennessee | OTHER |
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Asthma is a serious chronic health condition particularly in inner-city adolescents, who suffer disproportionately high asthma-related morbidity and mortality that place heavy economic burdens on families and society. There is a consensus that adverse asthma outcomes can be ameliorated by an individual's active engagement in adequate self-management. This multi-site randomized controlled study proposes to implement and evaluate a peer-led asthma self-management for adolescents (PLASMA) program that has demonstrated its feasibility and preliminary efficacy in a previous study. PLASMA will be implemented in three cities (Buffalo NY, Baltimore MD, and Memphis TN) that have particularly high rates of pediatric asthma and asthma-related morbidity, and are thus most likely to benefit from the program. PLASMA comprises three main components: (a) peer-leader training; (b) a one-day asthma camp where peer leaders will deliver manualized self-management content recommended by the national guidelines; and (c) bi-monthly peer-leader contacts. Specific aims are: (1) to evaluate the effectiveness of PLASMA in inner-city adolescents with asthma in improving quality of life (primary outcome), and asthma knowledge, attitudes, outcome expectations, self-efficacy, self-management skills, and asthma control, FEV1 (exploratory outcomes) over time, compared to a control group for whom adult leaders will deliver the same program content; (2) to examine the mediating effects of the exploratory outcomes on quality of life; (3) to examine the moderating effects of personal factors (e.g., age, sex, family support) on the intervention's primary and exploratory outcomes; (4) to evaluate the effects of PLASMA on study outcomes in peer leaders (16-20 years); and (5) to determine the economic impact of the intervention. These aims will be accomplished using a two-group randomized controlled trial with 378 adolescents (12-17 years) from the three cities (126 for each site). A total of 42 qualified peer leaders (14 in each site) will be enrolled based on adult nomination. Eligibility criteria for both peer leaders and adolescent learners include: a current asthma diagnosis; persistent asthma; absence of other chronic or mental illness; inner-city residence; and capability of verbal and written communication in English. Participants will provide data at enrollment (T1), camp (T2), and at 3-, 6-, 9-, 12-, and 15-months post-camp (T3-T7). Data will be analyzed using a multi-site hierarchical three-level linear mixed-effects model where level 1 represents repeated measures, level 2 = subject, and level 3 = site. To determine the economic impact of the program, investigator will measure the direct healthcare costs and total costs of the program, and perform net cost analyses for each type of costs. In addition, investigator will estimate cost-effectiveness ratios of the PLASMA group compared with the control.
Asthma, the most common pediatric chronic condition, is a serious problem for many adolescents. In 2010, nearly 11% of adolescents (2.7 million) ages 12 through 17 years in the US reported current asthma. This age cohort suffers greater asthma-related morbidity and mortality than younger children. Asthma disproportionately affects inner-city youth, where asthma severity has increased and achieving optimum asthma control has been elusive. Several factors including poor socioeconomic conditions, life stresses, and environmental triggers have been found to be associated with poorly controlled asthma in inner-city children. Programs targeting asthma in inner-city children have primarily focused on the modification of environmental factors and addressing disparity in healthcare access. Limited intervention efforts have been directed to address high inner-city asthma morbidity specifically in adolescents by promoting adequate self-management.
Dr. Rhee successfully completed an R21 (NR009837) where she designed an evidence-based peer-led asthma self-management for adolescents (PLASMA) program and tested its efficacy in a randomized parallel group design in 112 urban and suburban adolescents with persistent asthma. The PLASMA program was implemented at a one-day camp and involved monthly follow-ups by peer leaders. The program was well received by participants, and relative to adolescents who received an adult-led program, the PLASMA group reported better quality of life and asthma control and fewer asthma-related urgent office visits. Subgroup analysis revealed that the program was particularly effective for inner-city adolescents in improving asthma outcomes compared with suburban participants. Given the disproportionate burdens of asthma in inner-city youth and the program's compelling effects in this population, focusing on inner-city adolescents as a target of the PLASMA program is critical.
Building on this previous trial of efficacy, the overall goal of the proposed study is to evaluate the effectiveness and generalizability of the peer-led intervention, PLASMA, in improving asthma outcomes in inner-city adolescents from three metropolitan cities in the Northern, Eastern and Southern US with distinctive historical and cultural backgrounds. Multisite studies have been advocated as an effective approach to strengthening external validity as such studies afford the opportunity to assess the extent to which treatment effects are generalizable to different settings. Ascertaining generalizability across sites is important as it guides future translation of study findings into policy and practice. This study will also determine long-term sustainability of PLASMA effects and estimate the economic impact of the intervention. This multi-site study is significant in that it will target the understudied population, inner-city adolescents with asthma in three cities in the US, who present serious challenges to optimum asthma management.
Specific study aims are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Peer Led Asthma Self-Management | Active Comparator | Peer-led asthma self-management for adolescents : PLASMA will be implemented in small groups at a camp setting where paired peer-leaders will facilitate learning activities.Paired peer leaders will share and coordinate the responsibilities of facilitating group activities. Training content includes: Day 1: Asthma basics and prevention; Day 2: Asthma monitoring and management; Day 3: Communication/ psychosocial issue management/leadership training/hands-on practice in simulated peer-led group settings (role-play) |
|
| Adult Led Asthma Self-Management | Active Comparator | The adult led asthma self-management will take place within 2 weeks of the peer-led camp to minimize the history effect. Two healthcare professionals will attend peer-leader training sessions to become familiar with the program content, then lead instructional activities. As in PLASMA, adult leaders will base their instruction on the program manual to ensure comparable program content. Adult leaders will adopt mainly a didactic format and skill demonstration. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PLASMA | Behavioral | A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. Group learning activities will closely align with the program manual (LTAA) that consists of three sessions. Participants will also learn and practice skills in using the peak flow meter, spacer and inhaler, daily symptom diary and asthma action plan. Besides instructional activities, participants will engage in recreational activities that each camp site. |
| Measure | Description | Time Frame |
|---|---|---|
| The Pediatric Asthma Quality of Life Questionnaire (PAQOL) | a 23-item instrument, 118 consists of three subdomains: activity limitation (5 items), emotional function (8 items), and symptoms (10 items). Higher scores indicate better levels of functioning. This scale has proved a valid and reliable measure of asthma-specific quality of life in adolescents. Mean scores are reported, and range from 1 to 7. Higher score indicating higher quality of life. | 15 months |
| Measure | Description | Time Frame |
|---|---|---|
| Adolescent Asthma Knowledge Questionnaire (AAK) | This 30-item instrument is a modification of the original 27-item questionnaire measuring children's knowledge of triggers and symptom identification and asthma management procedures. Total score range from 0 to 30, with higher score indicating greater knowledge. | 15 months |
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Inclusion Criteria:
Eligibility criteria for adolescent (camp) participants include:
> 2 days/week of daytime symptoms,
>3-4 times of nighttime awakening,
>2 days/week of SABA use, or
any interference with normal activities due to asthma (4) Investigators will include those with chronic health conditions except for those with conditions affecting respiratory system, heart disease, pneumonia, etc., and those with moderate to severe cognitive impairments; (5) primary residence located in the participating inner cities based on zip codes; and (6) ability to understand spoken and written English.
Eligibility criteria for peer leaders include:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Johns Hopkins University | Baltimore | Maryland | 21205 | United States | ||
| University at Buffalo |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34874404 | Derived | Rhee H, Love T, Wicks MN, Tumiel-Berhalter L, Sloand E, Harrington D, Walters L. Long-term Effectiveness of a Peer-Led Asthma Self-management Program on Asthma Outcomes in Adolescents Living in Urban Areas: A Randomized Clinical Trial. JAMA Netw Open. 2021 Dec 1;4(12):e2137492. doi: 10.1001/jamanetworkopen.2021.37492. | |
| 30213611 |
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Of 446 screened participants, 320 met eligibility criteria and were enrolled and randomized to one of the two arms. Of 72 screened peer-leaders, 51 met criteria and were enrolled as peer-leaders as outlined in the intervention arm of the study, for a total of 371 enrolled individuals.
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| ID | Title | Description |
|---|---|---|
| FG000 | Adult Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the adult-led control group. |
| FG001 | Peer Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the peer-led intervention group. |
| FG002 | Peer Leaders | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This group is the peer leaders who facilitated the Peer--led intervention group intervention. |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline - Enrollment |
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| Training - Peer Leaders Only |
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| Intervention - Camp |
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| 3 Month Follow Up |
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| 6 Month Follow Up |
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| 9 Month Follow Up |
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| 12 Month Follow Up |
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| 15 Month Follow Up |
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| ID | Title | Description |
|---|---|---|
| BG000 | Adult Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the adult-led control group. |
| Units | Counts |
|---|---|
| Participants |
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| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | The Pediatric Asthma Quality of Life Questionnaire (PAQOL) | a 23-item instrument, 118 consists of three subdomains: activity limitation (5 items), emotional function (8 items), and symptoms (10 items). Higher scores indicate better levels of functioning. This scale has proved a valid and reliable measure of asthma-specific quality of life in adolescents. Mean scores are reported, and range from 1 to 7. Higher score indicating higher quality of life. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
|
Study time frame of 15 months from baseline to final follow up with participants.
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Adult Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the adult-led control group. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Hyekyun Rhee PhD, RN, FAAN | University of Rochester School of Nursing | 585-276-3775 | Hyekyun_Rhee@urmc.rochester.edu |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| ICF | No | No | Yes | Informed Consent Form | Sep 20, 2017 | Dec 4, 2017 | ICF_001.pdf |
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Sep 25, 2014 | Apr 8, 2020 | Prot_SAP_002.pdf |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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Given the overt nature of the intervention, blinding either participants or investigators was not achieved although we did not inform participants of their group membership explicitly.
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|
| Attitude Toward Asthma Scale (ATA) |
This 13-item scale measures children's attitudes toward their asthma on a 5-point Likert-type scale. Mean score ranges from 1 to 5, with higher score indicating a more positive attitude. |
| 15 months |
| Asthma Self-Efficacy (ASE) | This 14-item instrument measured on a 5-point scale (from 1='not at all sure' to 5='completely sure') assesses a child's confidence in attack prevention (e.g., learning asthma self-management skills, correct use of medication) and attack management (e.g., control symptoms, decide which medication to use). A total score was computed, ranging from 14 and 70, with higher values indicating greater self-efficacy. | 15 months |
| Asthma Outcome Expectation Scale (AOE) | This 5 items scale measured on a 9-point scale from 'not all all (1)' to 'extremely (9)' assess the construct of "outcome expectations" derived from social cognitive theory. The average score was computed, ranging from 1 to 9, with higher scores suggesting more positive expectations about performing actions of asthma self-management. | 15 months |
| Asthma Prevention Index | This is one of 3 subscales of asthma self-management indices developed for adolescents with asthma. The prevention index consists of 11 items measured on a 3-point scale. An average score based on items 1-9 was computed, ranging from 1 to 3, with higher scores suggesting greater regularity of prevention steps. | 15 months |
| Asthma Management Index (AMI) | This is one of the 3 subscales of Asthma Self-Management Indices. This subscale (9 items total) measures the number of steps taken to manage symptoms once they occur, and two response options are given, 0=no and 1=yes. Items 1-4, 6, 8 & 9 were summed for a total count of management steps taken, with possible scores ranging from 0 to 7. The higher the sum scores, the greater the number of steps taken to manage symptoms. | 15 months |
| Asthma Management Self-efficacy Index | This is one of 3 subscales of asthma self-management indices developed for adolescents with asthma. The self-efficacy index consists of 14 items measured on a 6-point scale (1='I am very sure I could not'; 6='I am very sure I could'). An average score of all 14 items was computed, ranging from 1 to 6, with higher scores suggesting greater self-efficacy. | 15 months |
| Asthma Control Questionnaire (ACQ) | ACQ consists of 6-items measuring asthma control based on the frequency, severity, and types of symptoms, as well as degree of activity limitation, and use of SABA in the past 7 days. Each item was responded on a 6-point scale from 0 to 6. Average scores were computed, with higher scores indicating worse asthma control. | 15 months |
| Buffalo |
| New York |
| 14203 |
| United States |
| University of Rochester Medical Center | Rochester | New York | 14642 | United States |
| University of Tennessee | Memphis | Tennessee | 38163 | United States |
| Rhee H, Love T, Mammen J. Comparing Asthma Control Questionnaire (ACQ) and National Asthma Education and Prevention Program (NAEPP) asthma control criteria. Ann Allergy Asthma Immunol. 2019 Jan;122(1):58-64. doi: 10.1016/j.anai.2018.09.448. Epub 2018 Sep 11. |
| 29150074 | Derived | Rhee H, Love TM, Harrington D, Grape A. Comorbidity of atopy in urban adolescents with asthma. Ann Allergy Asthma Immunol. 2017 Nov;119(5):466-467. doi: 10.1016/j.anai.2017.08.017. No abstract available. |
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| BG001 | Peer Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the peer--led intervention group. |
| BG002 | Peer Leaders | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This group is the peer leaders who facilitated the Peer--led intervention group intervention. |
| BG003 | Total | Total of all reporting groups |
| years |
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| Sex: Female, Male | Count of Participants | Participants |
|
| Ethnicity (NIH/OMB) | Count of Participants | Participants |
|
| Race/Ethnicity, Customized | Count of Participants | Participants |
|
| OG001 | Peer Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the peer-led intervention group. |
| OG002 | Peer Leaders | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This group is the peer leaders who facilitated the Peer--led intervention group intervention. |
|
|
|
| Secondary | Adolescent Asthma Knowledge Questionnaire (AAK) | This 30-item instrument is a modification of the original 27-item questionnaire measuring children's knowledge of triggers and symptom identification and asthma management procedures. Total score range from 0 to 30, with higher score indicating greater knowledge. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | units on a scale | 15 months |
|
|
|
|
| Secondary | Attitude Toward Asthma Scale (ATA) | This 13-item scale measures children's attitudes toward their asthma on a 5-point Likert-type scale. Mean score ranges from 1 to 5, with higher score indicating a more positive attitude. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
|
|
|
|
| Secondary | Asthma Self-Efficacy (ASE) | This 14-item instrument measured on a 5-point scale (from 1='not at all sure' to 5='completely sure') assesses a child's confidence in attack prevention (e.g., learning asthma self-management skills, correct use of medication) and attack management (e.g., control symptoms, decide which medication to use). A total score was computed, ranging from 14 and 70, with higher values indicating greater self-efficacy. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
|
|
|
|
| Secondary | Asthma Outcome Expectation Scale (AOE) | This 5 items scale measured on a 9-point scale from 'not all all (1)' to 'extremely (9)' assess the construct of "outcome expectations" derived from social cognitive theory. The average score was computed, ranging from 1 to 9, with higher scores suggesting more positive expectations about performing actions of asthma self-management. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | units on a scale | 15 months |
|
|
|
|
| Secondary | Asthma Prevention Index | This is one of 3 subscales of asthma self-management indices developed for adolescents with asthma. The prevention index consists of 11 items measured on a 3-point scale. An average score based on items 1-9 was computed, ranging from 1 to 3, with higher scores suggesting greater regularity of prevention steps. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
|
|
|
|
| Secondary | Asthma Management Index (AMI) | This is one of the 3 subscales of Asthma Self-Management Indices. This subscale (9 items total) measures the number of steps taken to manage symptoms once they occur, and two response options are given, 0=no and 1=yes. Items 1-4, 6, 8 & 9 were summed for a total count of management steps taken, with possible scores ranging from 0 to 7. The higher the sum scores, the greater the number of steps taken to manage symptoms. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
|
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|
|
| Secondary | Asthma Management Self-efficacy Index | This is one of 3 subscales of asthma self-management indices developed for adolescents with asthma. The self-efficacy index consists of 14 items measured on a 6-point scale (1='I am very sure I could not'; 6='I am very sure I could'). An average score of all 14 items was computed, ranging from 1 to 6, with higher scores suggesting greater self-efficacy. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
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|
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| Secondary | Asthma Control Questionnaire (ACQ) | ACQ consists of 6-items measuring asthma control based on the frequency, severity, and types of symptoms, as well as degree of activity limitation, and use of SABA in the past 7 days. Each item was responded on a 6-point scale from 0 to 6. Average scores were computed, with higher scores indicating worse asthma control. | Number of participants analyzed included only those who had data collected at 15 months. | Posted | Mean | Standard Deviation | score on a scale | 15 months |
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| 0 |
| 152 |
| 0 |
| 152 |
| 0 |
| 152 |
| EG001 | Peer Led Asthma Self-Management | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This arm is the peer-led intervention group. | 0 | 168 | 0 | 168 | 0 | 168 |
| EG002 | Peer Leaders | PLASMA: A structured asthma self-management manual ("Let's Talk about Asthma [LTAA],"developed by the study team will be utilized in a camp like setting and administered by either peers or adults medical professionals. The manual adheres to the 2007 NAEPP Guidelines Training strategies will involve didactic sessions, discussion, demonstrations, and role-play. This group is the peer leaders who facilitated the Peer--led intervention group intervention. | 0 | 51 | 0 | 51 | 0 | 51 |
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| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .00 | A priori threshold for statistical significance is <.05. | partial eta squared | .15 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .00 | A priori threshold for statistical significance is <.05. | partial eta squared | .15 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .14 | A priori threshold for statistical significance is <.05. | partial eta squared | .06 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .43 | A priori threshold for statistical significance is <.05. | partial eta squared | .03 | 2-Sided | Superiority |
| Mixed Models Analysis | .024 | Slope | -.203 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .00 | A priori threshold for statistical significance is <.05. | partial eta squared | .12 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .04 | A priori threshold for statistical significance is <.05. | partial eta squared | .07 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .23 | A priori threshold for statistical significance is <.05 | partial eta squared | .04 | 2-Sided | Superiority |
| For each model, partial eta squared (η2) was reported as the effect size for the overall change over time. Partialη2 is the proportion of variance explained by a given variable out of the variance remaining after excluding variance explained by other predictors. Partial η2> 0.14 indicates large effects, while η2= 0.06 to 0.14 medium and < 0.06 small effects | Mixed Models Analysis | .00 | A priori threshold for statistical significance is <.05 | partial eta squared | .12 | 2-Sided | Superiority |
| Mixed Models Analysis | .004 | Slope | -.294 | 2-Sided | Superiority |
| Mediator analysis of AMI-SEI subscale on ACQ total | Sobel | .0093 | Sobel Statistic | -2.3505 | 2-Sided | Superiority |