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| Name | Class |
|---|---|
| Vitalgrana Pomegranate SL | UNKNOWN |
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The purpose of this study is to evaluate modifications of plasma protein carbonyls and malondialdehyde levels in endurance-based athletes after three weeks of pomegranate juice consumption.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Arm that followed all the protocols with the exception of the pomegranate juice intake. | |
| Pomegranate Juice | Experimental | Arm that followed all the protocols and the pomegranate juice intake. |
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| Pomegranate Juice Dilution | Experimental | Arm that followed all the protocols and the pomegranate juice dilution (1:1) intake. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pomegranate juice | Dietary Supplement | Intake of 200 ml of pomegranate juice or pomegranate juice dilution during 21 days after exercise. |
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| Measure | Description | Time Frame |
|---|---|---|
| Protein carbonyls levels changes in plasma | Protein carbonyl derivatives were determined using an adaptation of the colorimetric method published in Levine et al. (1994) based in the formation of a stable 2,4-dinitrophenyl (DNP) hydrazone product after the addition of 2,4-dinitrophenylhydrazine (DNPH) to tha plasma. Protein carbonyls were calculated as nmoles·mg-1 protein | day 0 and 22 |
| Malondialdehyde levels changes in plasma | Malondialdehyde was determined by high pressure liquid chromatography (HPLC) with fluorescence detection according to the method described by Laporta et al. (2007). Malondialdehyde levels were calculated as nmoles·g-1 protein | day 0 and 22 |
| Measure | Description | Time Frame |
|---|---|---|
| Blood biochemical parameters changes in plasma | Blood biochemical parameters is a composite outcome measure consisting in circulating plasma glucose (mg·dL-1), HDL-cholesterol (mg·dL-1), triglycerides (mg·dL-1), ferritin (ng·mL-1), lactate (mg·dL-1), sodium (mEq·L-1), potassium (mEq·L-1), creatine kinase (U·L-1), aspartate aminotransferase (U·L-1) and alanine aminotransferase (U·L-1) were analyzed through biochemistry methods. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Enrique Roche, PhD | University Miguel Hernández | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10799367 | Result | Aviram M, Dornfeld L, Rosenblat M, Volkova N, Kaplan M, Coleman R, Hayek T, Presser D, Fuhrman B. Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice. Am J Clin Nutr. 2000 May;71(5):1062-76. doi: 10.1093/ajcn/71.5.1062. | |
| 21659887 |
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|
| day 0 and 22 |
| C-reactive protein levels changes in plasma | Determination by immunoassay of C-reactive protein (ng·mL-1) levels in plasma. | day 0 and 22 |
| Soluble E-selectin levels changes in plasma | Determination by immunoassay of soluble E-selectin (ng·mL-1) levels in plasma. | day 0 and 22 |
| Trombold JR, Reinfeld AS, Casler JR, Coyle EF. The effect of pomegranate juice supplementation on strength and soreness after eccentric exercise. J Strength Cond Res. 2011 Jul;25(7):1782-8. doi: 10.1519/JSC.0b013e318220d992. |