Genetic and Epigenetic Mechanisms Underlying Cocoa Health Benefits

Genetic and Epigenetic Mechanisms Underlying Cocoa Health Benefits

Evaluate if gene expression changes in SOD2 explain the health benefits of high polyphenols cocoa

Evaluate if gene expression changes in SOD2 explain the health benefits of high polyphenols cocoa.

Inclusion Criteria:

• Healthy adults
• BMI between 18.5 and 30 kg/m2
• Sedentary to moderate physical activity habits

Exclusion Criteria:

• Consumption of dietary supplements, antioxidants or anti-inflammatory medication, such as aspirin, ibuprofen, naproxen, or any medication that can affect the study outcomes
• Actively smoking
• Suspected abuse of alcohol or illicit drugs
• Significant illness within two weeks prior to study start or any active systemic infection or medical condition that may require treatment or therapeutic intervention during the study
• Subject who cannot be expected to comply with study procedures
• Currently participating or having participated in another clinical trial during last 4 weeks prior to the beginning of this study
• Consumption of chocolate or its derivates 24 hours before the blood sample taken