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| Name | Class |
|---|---|
| Columbia University | OTHER |
| University of Zurich | OTHER |
| James S McDonnell Foundation | OTHER |
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Stroke often results in limitation of arm movements, from which many people do not fully recover. We believe that early and intensive therapy is important to enhance recovery of arm movements after stroke. We are doing this research study to see how much arm movements improve with intensive therapy in patients have had a stroke in the past 6 weeks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Device-assisted therapy | Active Comparator | 30 hours of therapy with the ArmeoPower device, a commercially available device for arm rehabilitation |
|
| Therapy-based occupational therapy | Active Comparator | 30 hours of conventional occupational therapy that emphasizes task-oriented training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Device-assisted therapy | Behavioral |
| ||
| Therapy-based occupational therapy |
| Measure | Description | Time Frame |
|---|---|---|
| Fugl-Meyer Upper Extremity (FM-UE) | Change in arm impairment, measured by FM-UE | from baseline to day 3 post-training |
| Measure | Description | Time Frame |
|---|---|---|
| Fugl-Meyer Upper Extremity (FM-UE) | Change in arm impairment, measured by FM-UE | from baseline to day 90 post-training |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| John W. Krakauer, MD | Johns Hopkins University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Johns Hopkins University | Baltimore | Maryland | 21205 | United States | ||
| Columbia University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33745372 | Derived | Krakauer JW, Kitago T, Goldsmith J, Ahmad O, Roy P, Stein J, Bishop L, Casey K, Valladares B, Harran MD, Cortes JC, Forrence A, Xu J, DeLuzio S, Held JP, Schwarz A, Steiner L, Widmer M, Jordan K, Ludwig D, Moore M, Barbera M, Vora I, Stockley R, Celnik P, Zeiler S, Branscheidt M, Kwakkel G, Luft AR. Comparing a Novel Neuroanimation Experience to Conventional Therapy for High-Dose Intensive Upper-Limb Training in Subacute Stroke: The SMARTS2 Randomized Trial. Neurorehabil Neural Repair. 2021 May;35(5):393-405. doi: 10.1177/15459683211000730. Epub 2021 Mar 20. | |
| 33175411 |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Behavioral |
|
| New York |
| New York |
| 10032 |
| United States |
| University of Zurich | Zurich | Switzerland |
| Derived |
| Elsner B, Kugler J, Pohl M, Mehrholz J. Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke. Cochrane Database Syst Rev. 2020 Nov 11;11(11):CD009645. doi: 10.1002/14651858.CD009645.pub4. |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |