Effect of an Anti-spasmodic Suppository to Improve Comfort After Urologic Surgery

Pre-operative Administration of a Muscarinic Antagonist for Elective Cystoscopy Patients

This study evaluates the ability of a belladonna and opium suppository given prior to surgery to improve bladder comfort after surgery for patients who are having elective ureteroscopy surgery.

Belladonna and opium suppositories are administered postoperatively to relieve bladder discomfort usually caused by bladder spasms. The onset of action of the suppository is 30-60 minutes. Bladder spasms are more likely to occur following uteroscopy procedures. The spasms result in a felt desire to void, even when there is no urine in the bladder. The spasms can produce pain or a sense of severe urgency.

By administering a belladonna and opium suppository at the beginning of surgery, it is hoped that there will be a decrease in the incidence of bladder spasms, increased comfort and less need for additional medications.

Inclusion Criteria:

• Patients from one urology practice schedule for elective uteroscopy.

Exclusion Criteria:

• Patients with pre-operative indwelling catheter or urinary stent.
• Patients who report any allergy to belladonna or opium.