Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to assess safety, PK/PD and Urate Lowering Effect of URC102 in gout patients with hyperuricemia
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | Placebo x 2weeks |
|
| URC102 0.25mg | Placebo Comparator | 0.25mg URC102 x 2weeks |
|
| URC102 0.5mg | Experimental | 0.5mg URC102 x 2weeks |
|
| URC102 1.0mg | Placebo Comparator | 1.0mg URC102 x 2weeks |
|
| URC102 2.0mg | Placebo Comparator | 2.0mg URC102 x 2weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| URC102 0.25mg | Drug |
| ||
| URC102 0.5mg |
| Measure | Description | Time Frame |
|---|---|---|
| Trend of serum uric acid reduction and trend of serum uric acid levels | Frequency of patients with serum uric acid level reduced to < 6.0 mg/dL and < 5.0 mg/dL at each measurement | weekly for 3weeks |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| JW Pharmaceutical | Seoul | Seocho-dong | 137-864 | South Korea |
Not provided
| ID | Term |
|---|---|
| D006073 | Gout |
| D033461 | Hyperuricemia |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D000070657 | Crystal Arthropathies |
Not provided
Not provided
| ID | Term |
|---|---|
| C000706548 | URC102 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| URC102 1.0mg | Drug |
|
| URC102 2.0mg | Drug |
|
| placebo | Drug |
|
| D012216 |
| Rheumatic Diseases |
| D011686 | Purine-Pyrimidine Metabolism, Inborn Errors |
| D008661 | Metabolism, Inborn Errors |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |