A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain

A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain

The purpose of this study is to determine whether dexmedetomidine added to morphine is effective in the treatment of chronic cancer pain.

We conduct the study in Cukurova University Faculty of Medicine Research Hospital after obtaining ethics committee approval and patient's informed consent. Patients with cancer pain are allocated into two group to receive Patient Controlled Analgesia with morphine or morphine plus dexmedetomidine.

Inclusion Criteria:

• patients with chronic cancer pain
• between 20-80 years old age

Exclusion Criteria:

• the presence of severe systemic disease(cardiac, pulmonary, hepatic or renal)
• psychiatric or neurologic disease
• unable to communicate verbally
• nausea and vomiting
• patient's refusal