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The primary purpose was to describe the acid base balance of ICU patients with severe hypoalbuminemia using Stewart's approach for acid base disorders, before and after an human albumin perfusion.
Prospective study, for ICU patient with severe hypoalbuminemia < 20g/L, determining biological parameters from Stewart approach for acid base disorders (pH, SIDe, SIDa, SIG, Atot, PaCO2) before, and at 1hour, 2hours and 24 hours after a 200mL 20% human albumin perfusion (the consensus conference ANAES of 1995 recommands to correct hypoalbuminemia below 20g/L).
Clinical parameters (respiratory, haemodynamic, neurologic) were also collected at the same times.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| hypoalbuminemia | The primary purpose was to describe the acid base balance of ICU patients with severe hypoalbuminemia using Stewart's approach for acid base disorders, before and after an human albumin perfusion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| stewart approach | Other | Prospective study, for ICU patient with severe hypoalbuminemia < 20g/L, determining biological parameters from Stewart approach for acid base disorders (pH, SIDe, SIDa, SIG, Atot, PaCO2) before, and at 1hour, 2hours and 24 hours after a 200mL 20% human al Clinical parameters (respiratory, haemodynamic, neurologic) were also collected at the same times. |
| Measure | Description | Time Frame |
|---|---|---|
| changes in pH and independent pH determinants using Stewart approach | at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion. |
| Measure | Description | Time Frame |
|---|---|---|
| changes in neurologic parameters | at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion. | |
| changes in hemodynamic parameters | at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion. |
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Inclusion Criteria:
Exclusion Criteria:
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ICU patients with severe hypoalbuminemia
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| Name | Affiliation | Role |
|---|---|---|
| Julien PASCAL | University Hospital, Clermont-Ferrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Clermont-Ferrand | Clermont-Ferrand | 63003 | France |
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|
| changes in respiratory parameters | at 1 hour, 2 hours and 24 hours after a 200mL of 20% human albumin perfusion. |
| ID | Term |
|---|---|
| D034141 | Hypoalbuminemia |
| ID | Term |
|---|---|
| D007019 | Hypoproteinemia |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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