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| ID | Type | Description | Link |
|---|---|---|---|
| 11/YH/0404 | Other Identifier | Research Ethics Committee |
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Spread of cancer to the spinal column is a growing problem in patients with cancer. It can cause a number of problems including pain, instability and neurologic problems. If left untreated, progressive weakness, numbness and bladder/bowel disturbance occurs. The aim of treatment is to help with pain and to reduce the risk of these neurological problems. This treatment has traditionally been radiotherapy to the spine. Surgery has always meant large open operations with a long recovery time and significant risk of complications. There has been new technology that has allowed less invasive operations to take place to stabilise the spine. The aim is to relieve the pressure on the spinal cord in addition to stabilising the spinal cord. These techniques are called 'minimally invasive' and include surgical techniques such as cement augmentation and percutaneous instrumentation.
The aim of this study is to compare traditional open operations with these new minimally invasive techniques to see if they do result in reduced complications and quicker recovery in addition to achieving the goals of surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Posterior percutaneous instrumentations | Experimental |
| |
| Traditional open surgery with pedicle screw fixation | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Open fixation | Procedure |
| ||
| Keyhole surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Visual analogue pain (VAS) scores | 3 months | |
| Visual analogue pain (VAS) scores | 6 months | |
| Visual analogue pain (VAS) scores | 1 year | |
| Visual analogue pain (VAS) scores | 2 years | |
| Oswestry disability score | 3 months | |
| Oswestry disability score | 6 months | |
| Oswestry disability score | 1 year | |
| Oswestry disability score | 2 years | |
| EuroQoL Questioonaire (EQ-5D) | 3 months | |
| EuroQoL Questioonaire (EQ-5D) | 6 months | |
| EuroQoL Questioonaire (EQ-5D) | 1 year | |
| EuroQoL Questioonaire (EQ-5D) | 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| Procedure |
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