This is a randomized ,opened, prospective controlled trial of clinical effectiveness for Icotinib as the adjunctive treatment after surgery in stage I-IIIB lung adenocarcinoma patients with epidermal growth factor receptor gene mutation

In this trial the investigators will enlist 100 patients who accepted surgery and with epidermal growth factor receptor gene mutation,these patients will be divided into 2 groups (chemotherapy group and Icotinib group),compare the PFS,RFS,OS after 5 years follow up

Inclusion Criteria:

• 18-75 years old
• Lung adenocarcinoma patients with epidermal growth factor receptor gene mutation,stage I-IIIB after surgery
• The patients' Eastern Cooperative Oncology Group scores are ≤ 0-2

Exclusion Criteria:

• Mismatch conditions above
• Have used other anti-cancer therapy drug before the trial and may influence the outcome