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The planned research project is a prospective population-based cohort study, similar to the well-known Framingham study in the United States. So far, there is no similar research project in Switzerland.
It is planned to examine of three Swiss municipalities. Recruitment in a first Swiss municipality (Lostallo/Cama GR) started 2014 and ended in 2019. Overall, 496 participants were recruited in this municipality. The five-year follow-up in this municipality started in 2019. It is planned to start recruitment in a second Swiss municipality (Uznach SG) in 2020.
The examinations embrace a broad spectrum of measurements (for details the investigators refer to the published study protocol).
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Other |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiovascular events | Cardiovascular events (i.e. stroke, myocardial infarction) will be assessed using questionnaires and case records. | 10 years |
| Heart function | Heart function will be assessed using questionnaires for symptoms, clinical examination and measurement of electromechanical activation time. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in cardiovascular risk factors | Cardiovascular risk factors will be assessed using validated measurements. | 10 years |
Inclusion Criteria:
Exclusion Criteria:
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Population of four Swiss municipalities
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Paul Erne, MD | Contact | paul.erne@erne-net.ch | ||
| Andreas W Schoenenberger, MD | Contact | Andreas.Schoenenberger@insel.ch |
| Name | Affiliation | Role |
|---|---|---|
| Paul Erne, MD | Hypertension Excellence Centre Lucerne | Study Chair |
| Andreas W Schoenenberger, MD | University Department of Geriatrics, University of Bern | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Linth Hospital | Recruiting | Uznach | Canton of St. Gallen | 8730 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36152116 | Derived | Pusterla L, Radovanovic D, Muggli F, Erne P, Schoenenberger AW, Schoenenberger-Berzins R, Parati G, Suter P, Lava SAG, Gallino A, Bianchetti MG. Impact of Cardiovascular Risk Factors on Arterial Stiffness in a Countryside Area of Switzerland: Insights from the Swiss Longitudinal Cohort Study. Cardiol Ther. 2022 Dec;11(4):545-557. doi: 10.1007/s40119-022-00280-8. Epub 2022 Sep 24. | |
| 34581550 |
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| 10 years |
| Cognitive function | Cognitive function will be assessed using validated instruments. | 10 years |
| Kidney function | Kidney function will be assessed using laboratory measurements. | 10 years |
| Autonomy | Autonomy wil be assessed using validated instruments. | 10 years |
| Nursing home admission | Nursing home admissions will be assessed using standardized questions. | 10 years |
| Paolo Suter, MD |
| University of Zurich |
| Principal Investigator |
| Franco Muggli, MD | Swiss Society of Hypertension | Principal Investigator |
| Renate Schoenenberger, MD | Hypertension Excellence Centre Lucerne | Principal Investigator |
| Pierre-Alexandre Krayenbühl, MD | Linth Hospital | Principal Investigator |
| Cama | Recruiting | Cama | Kanton Graubünden | CH-6557 | Switzerland |
|
| Lostallo | Recruiting | Lostallo | Kanton Graubünden | CH-6558 | Switzerland |
|
| Derived |
| Schoenenberger AW, Radovanovic D, Muggli F, Suter PM, Schoenenberger-Berzins R, Parati G, Bianchetti MG, Gallino A, Erne P. Prevalence of ideal cardiovascular health in a community-based population - results from the Swiss Longitudinal Cohort Study (SWICOS). Swiss Med Wkly. 2021 Sep 28;151:w30040. doi: 10.4414/smw.2021.w30040. eCollection 2021 Sep 27. |
| 27895066 | Derived | Schoenenberger AW, Muggli F, Parati G, Gallino A, Ehret G, Suter PM, Schoenenberger-Berzins R, Resink TJ, Erne P. Protocol of the Swiss Longitudinal Cohort Study (SWICOS) in rural Switzerland. BMJ Open. 2016 Nov 28;6(11):e013280. doi: 10.1136/bmjopen-2016-013280. |